Fexo 120mg Tablet is a member of the antihistamine or anti-allergic medicine class. It is mostly employed to treat different allergies. An allergic reaction is an immune system reaction to outside substances that are usually not detrimental to your body. These alien substances are referred to as "allergens." The severity of allergies varies from individual to person. Some people may have dietary and seasonal allergies like hay fever. Others might, however, have allergies to pet dander or pollen.
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Fexofenadine is a second-generation antihistamine, which means that it has a lower risk of causing drowsiness and other central nervous system side effects compared to first-generation antihistamines like diphenhydramine and chlorpheniramine.
Fexofenadine is a substrate of the drug transporter P-glycoprotein (P-gp), which means that it may interact with other drugs that inhibit or induce P-gp. Examples of P-gp inhibitors include ketoconazole, erythromycin, and grapefruit juice, while P-gp inducers include rifampin and St. John's wort. These drugs may increase or decrease the blood levels of fexofenadine, leading to potential drug interactions and changes in efficacy or toxicity.
Fexofenadine is also metabolized by the liver enzyme CYP3A4 but to a lesser extent than some other antihistamines like terfenadine and astemizole. However, caution should still be exercised when co-administering fexofenadine with strong CYP3A4 inhibitors like clarithromycin and itraconazole.
The recommended dose of fexofenadine is usually 120mg once daily for adults and children over 12 years of age but may be adjusted based on individual needs and tolerability. The dispersible tablet should be dissolved in water before use, while the syrup and suspension should be shaken well before measuring and administering the dose. The duration of treatment may vary depending on the underlying condition and response to therapy but should be guided by the healthcare provider.
Avoid alcohol consumption while taking Fexo 120mg Tablet as it may cause increased drowsiness.
Fexo 120mg Tablet is generally not recommended for use in pregnant women unless considered clearly necessary. Consult your doctor before taking it.
Fexo 120mg Tablet is not recommended for use in breastfeeding women. Consult your doctor for advice.
Do not drive or operate machines if Fexo 120mg Tablet makes you dizzy or sleepy. Consult your doctor before taking Fexo 120mg Tablet
Fexo 120mg Tablet is to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.
Fexo 120mg Tablet is to be taken with caution, especially if you have a history of Liver diseases/conditions. The dose may have to be adjusted by your doctor.
Used in adults and children (aged above 12 years) to provide:
Fexo 120 works by blocking the actions of H1 histamine receptors (the chemical substance responsible for allergic reaction) that results in preventing the occurrence of seasonal allergic rhinitis and idiopathic urticaria thus providing relief from the symptoms associated with both conditions.
Fexo 120mg Tablet is an anti-allergy medicine used in the treatment of allergic symptoms such as runny nose, congestion or stuffiness, sneezing, itching, swelling, and watery eyes. It also helps treat skin allergies with itching, redness, or swelling.
Antihistamine Fexofenadine Hydrochloride works as an H1-receptor antagonist in the peripheral nervous system. It is readily absorbed after oral administration and reaches its peak plasma concentration in two to three hours. It seems to be unable to cross the blood-brain barrier.
Fexofenadine dosage recommendations for seasonal allergic rhinitis and chronic idiopathic urticaria vary based on age and renal function.
Fexo 120mg Tablet may interact with several medications, including midodrine (used to treat low blood pressure), ketoconazole (used to treat fungal infections), erythromycin, and rifampicin (antibiotics), ritonavir or lopinavir (medications used to treat HIV infection), theophylline (a respiratory disease medicine), pseudoephedrine (a decongestant), and indigestion remedies containing aluminum or magnesium.
Fexofenadine Hydrochloride's plasma levels increased when coupled with erythromycin or ketoconazole. Antacids that contain aluminum and magnesium hydroxide inhibit Fexo absorption.
Consuming large amounts of alcohol and certain fruit juices, such as grapefruit, orange, and apple, may decrease the levels of Fexo 120mg Tablets in the body. Therefore, it is important to avoid consuming large amounts of alcohol and these fruit juices while taking this medication.
Fexo 120mg Tablet is contraindicated in patients with liver or kidney disease, heart problems, and epilepsy (fits). It is important to inform your doctor about any medical conditions that you have before starting this medication.
Fexofenadine Hydrochloride is classified as a Category C medication by the US Food and Drug Administration (FDA) for use during pregnancy. This means that it is not known whether this medication can harm an unborn baby if taken during pregnancy. It is also not known whether fexofenadine hydrochloride can pass into breast milk and harm a nursing infant. Therefore, the use of fexofenadine hydrochloride should be avoided during pregnancy and breastfeeding unless the potential benefits to the mother outweigh the potential risks to the fetus or infant. It is important to discuss any concerns with your doctor before taking fexofenadine hydrochloride during pregnancy or while breastfeeding.
Additionally, patients should inform their doctor of any other medications, supplements, or herbal remedies they are taking before starting Fexo 120mg Tablet, as there may be potential drug interactions. Patients should also avoid consuming large amounts of alcohol or fruit juices, including grapefruit, orange, and apple juice, as these may affect the levels of Fexo 120mg Tablet in the body. If any side effects are experienced while taking this medication, such as drowsiness, fever, skin rashes, weakness, or persistent symptoms, patients should consult their doctor immediately. Finally, patients should not share their medication with others, even if their symptoms appear similar.
Store in a cool and dry place away from sunlight. Keep out of children's reach.
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