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Information about Alatrol Syrup 60ml
Indications of Alatrol 60 ml
It's used to treat seasonal and perennial allergic rhinitis symptoms. It's also used to treat the cutaneous symptoms of chronic idiopathic urticaria and allergen-induced asthma
Cetirizine hydrochloride is an effective H1 receptor antagonist without any significant anticholinergic or antiserum effects. At the pharmacologically active dose level, it produces almost no drowsiness and does not cause behavioral changes. It inhibits the early stages of histamine-mediated allergic reactions and also reduces the migration of inflammatory cells and the release of mediators related to the later stages of allergic reactions.
Pharmacokinetics: Cetirizine 10 mg reaches a maximum plasma concentration of 257 mcg / L (980 mcg / L in children) within 1 hour after administration. Food does not affect the degree of absorption, but may slightly slow down the rate. A maximum blood concentration of 0.3 µg / ml was reached between 30 and 60 minutes after administration of a 10 mg dose of cetirizine. Its plasma half-life is approximately 11 hours. The absorption from one topic to another is very consistent. Its renal clearance rate is 30 ml/min and its excretion half-life is approximately 9 hours.
Dosage & Administration
Adults and Children 6 years and older: 1 tablet or 2 teaspoonfuls daily (or 1 teaspoonful twice daily).
Children 2-6 years: 1 teaspoonful once daily or 1/2 teaspoonful twice daily.
Children 6 months to 2 years: 1/2 teaspoonful once daily. The dose in children 12-23 months of age can be increased to a maximum dose of 1/2 teaspoonful every 12 hours.
Interaction of Alatrol 60 ml
Theophylline, Azithromycin, Pseudoephedrine, Ketoconazole, and Erythromycin, as well as other medications, have been determined to have no clinically relevant drug interactions.
It is contraindicated in patients with a history of hypersensitivity to Cetirizine or hydroxyzine.
Side Effects of Alatrol 60 ml
The most common side effect that occurred more frequently on Cetirizine is somnolence.
Pregnancy & Lactation
Cetirizine Hydrochloride is classified as a pregnancy category B by the US Food and Drug Administration. However, no suitable and well-controlled studies on pregnant women have been conducted. Because animal reproduction studies do not always predict human response, this medication should only be used during pregnancy if absolutely necessary. Human milk has been found to contain cetirizine hydrochloride. When Cetirizine Hydrochloride is given to a breastfeeding woman, caution should be observed.
Precautions & Warnings
Caution should be exercised when driving a car or operating heavy machinery.
Keep in a dry place away from light and heat. Keep out of the reach of children.
Ratings & Reviews
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