Vitamin D3 is absorbed primarily from the small intestine and transported to the liver, where it is converted into 25-hydroxyvitamin D3 (calcidiol). It is subsequently converted in the kidneys to 1,25-dihydroxyvitamin D3 (calcitriol), the biologically active form of Vitamin D.
Calcitriol binds to Vitamin D receptors (VDRs) present in various tissues and promotes intestinal absorption of calcium and phosphate. These minerals are essential for normal bone mineralization and maintenance of healthy calcium levels.
Because Vitamin D3 is fat-soluble, it can be stored in body tissues, particularly fat and muscle. Vitamin D metabolites are eliminated mainly through faeces and urine.
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Aristo D3 contains Vitamin D3 (Cholecalciferol), an essential fat-soluble vitamin required for the normal absorption and utilization of calcium and phosphate. Adequate Vitamin D3 supports healthy bones and teeth and helps prevent deficiency-related conditions such as rickets and osteomalacia.
Vitamin D3 deficiency may occur in people with limited exposure to sunlight, inadequate dietary intake, or increased nutritional requirements. Maintaining adequate Vitamin D levels is particularly important during periods of growth, pregnancy, breastfeeding, and in older adults.
Vitamin D3 also contributes to normal immune system function.
Vitamin D3 may be used during pregnancy when medically indicated. The appropriate dose depends on the mother's Vitamin D status and individual clinical requirements. Pregnant women should use high-dose Vitamin D3 only under the supervision of a healthcare professional.
Vitamin D3 and its metabolites can pass into breast milk. When additional Vitamin D3 is prescribed to a breastfeeding mother or breastfed infant, the total Vitamin D intake from all sources should be considered to avoid excessive supplementation.
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At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.