Xfin 1% Cream

Uses of Xfin 1% Cream

• Fungal skin infections

How to use Xfin 1% Cream

• Xfin 1% Cream is for external use only.
• Use Xfin 1% Cream in the dose and duration as advised by your doctor.
• Check the label for directions before use.
• Clean and dry the affected area and apply the cream.
• Wash your hands after applying, unless your hands are the affected area.

How Xfin Xfin 1% Cream

Xfin is an antifungal medication that treats skin infections. It works by killing the fungi on the skin by destroying their cell membrane.

What if you forget to take Xfin 1% Cream ?

If you miss a dose of Xfin, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Side Effects of Xfin 1% Cream

• Application site reactions (burning, irritation, itching, and redness)
• Skin peeling
• Headache
• Diarrhea
• Rash
• Indigestion
• Abnormal liver enzyme
• Itching
• Taste change
• Nausea
• Abdominal pain
• Flatulence

Quick Suggestions:

• Xfin 1% Cream aids in treating skin infections brought on by a variety of fungi.
  Even if you feel better, complete the entire course of therapy.
• The skin's usual hue may not return for several months after the infection has cleared up.
• Apply enough to completely cover the afflicted region and 1 inch of the skin around it.
• Your skin can become more sun-sensitive as a result. When outside, use protective gear and broad-spectrum sunscreen.
• Don't get any in your mouth, nose, or eyes. If exposure happens accidentally, immediately rinse with plenty of water.
• After four weeks of therapy, let your doctor know if the infection has not disappeared.

Indications of Xfin 1% Cream

Xfin 1% Cream is used to treat a number of fungal skin diseases, including jock itch, athlete's foot, and ringworm. Additionally, pityriasis (tinea versicolor), a fungal infection that results in the lightening or darkening of the skin on the neck, chest, arms, or legs, is treated with this medicine. The antifungal terbinafine inhibits the development of fungus.

Pharmacology

By blocking the Squalene Epoxidase enzyme, the antifungal allylamine terbinafine prevents the production of ergosterol, which is crucial for the structure of fungal cell membranes. Instead of ergosterol deficiency, this results in fungal cell death mostly as a result of enhanced membrane permeability brought on by high amounts of squalene accumulation. Depending on the fungus species examined in vitro and the medicine concentration, terbinafine hydrochloride may be fungicidal. On the other hand, it is uncertain what use in vitro findings will have in clinical settings. Terbinafine has been shown to be effective against the majority of strains of the following bacteria both in vitro and in clinical infections: Trichophyton Menta Menta Tricophyton Tricophyton menta. 

Dosage & Administrations of Xfin 1% Cream

Terbinafine Cream: 

• Terbinafine Cream ( Xfin 1% Cream) can be applied once or twice daily.
• Cleanse and dry the affected areas thoroughly before the application of the Terbinafine Cream.
• Apply the cream to the affected skin and the surrounding area in a thin layer and rub it lightly.
• In the case of intertriginous infections (submammary, interdigital, intergluteal, inguinal) the application may be covered with a gauze strip, especially at night.

The likely durations of treatment are as follows:

• Tinea corporis, cruris: 1 to 2 weeks
• Tinea pedis: 1 week
• Cutaneous candidiasis: 2 weeks
• Pityriasis Versicolor: 2 weeks

Relief of the clinical symptoms usually occurs within a few days. Irregular use or premature discontinuation of treatment carries the risk of recurrence. If there are no signs of improvement after two weeks, the diagnosis should be verified.

Interaction

Terbinafine inhibits the CYP450 2D6 isozyme in vivo, according to research. Tricyclic antidepressants, selective serotonin reuptake inhibitors, beta-blockers, antiarrhythmics class 1C (e.g., flecainide and propafenone), and monoamine oxidase inhibitors Type B are among the drugs processed mostly by the CYP450 2D6 isozyme. Co-administration of terbinafine should be done with caution, and the dose of the 2D6-metabolized medication may need to be reduced.

Contraindications

Terbinafine Cream is not recommended for people who are hypersensitive to Terbinafine.

Pregnancy & Lactation

• Terbinafine cream has been shown to have no negative effects on fetal toxicity and fertility in animals.
• There is no clinical experience with terbinafine in pregnant women; consequently, terbinafine should not be used unless the possible benefits outweigh the potential risks.
• Terbinafine is secreted in breast milk, so mothers who are breastfeeding should avoid terbinafine medication.

Precautions & Warnings

• Inform your doctor or pharmacist before using terbinafine if you have any sensitivities to it, other allylamine antifungals (such as naftifine), or other substances. Inactive chemicals in this product have the potential to trigger allergic reactions or other issues. To learn more, speak with your pharmacist.
• Before taking this product, speak to your doctor or pharmacist if you have any health issues.
• This drug should only be taken during pregnancy if absolutely necessary. Describe the advantages and disadvantages of your doctor.
• When taken orally, other formulations of this medicine enter into breast milk. When administered to the skin, this medication may transfer into breast milk, however, this is uncertain. Before breastfeeding, speak with your doctor.

Storage Conditions

Protect from light and moisture by storing in a cool, dry place below 25°C. Keep out of children's reach.