â 100% Authentic Product
đī¸ Currently Viewing 848
Liglimet 2.5mg/500mg Tablet 6pcs
Liglimet is indicated as an adjunct to diet and exercise to improve blood glucose control in adults with type 2 diabetes mellitus, when treatment with both Linagliptin and Metformin is appropriate.
100% Genuine Products, Guaranteed
Safe & Secure Payments, Always
Fast, Secure & Efficient Delivery
Proper Packaging
Cash on Delivery - All over Bangladesh
Regular Delivery - 12-24 Hours, Dhaka City*- Regular Delivery - 24-48 Hours, All Over Bangladesh*
āĻĢā§āĻ°āĻŋ āĻĄā§āĻ˛āĻŋāĻāĻžāĻ°āĻŋāĻ - ā§¯ā§¯ā§¯ āĻāĻžāĻāĻž+ āĻ
āĻ°ā§āĻĄāĻžāĻ°ā§, āĻĸāĻžāĻāĻž
āĻļāĻšāĻ°ā§- āĻĢā§āĻ°āĻŋ āĻĄā§āĻ˛āĻŋāĻāĻžāĻ°āĻŋāĻ - ā§¨ā§¯ā§¯ā§¯ āĻāĻžāĻāĻž+ āĻ
āĻ°ā§āĻĄāĻžāĻ°ā§, āĻĸāĻžāĻāĻžāĻ°
āĻŦāĻžāĻšāĻŋāĻ°ā§
â Description:
Linagliptin
DPP-4 inhibitor: Prevents degradation of incretin hormones (GLP-1 and GIP).
Enhances glucose-dependent insulin secretion.
Reduces glucagon release from Îą-cells.
Improves blood glucose without causing hypoglycemia.
Metformin Hydrochloride
A biguanide class oral antidiabetic.
Reduces hepatic glucose production, slows glucose absorption, and enhances peripheral glucose uptake.
Does not cause hypoglycemia when used alone.
Relevant Products / āĻĒā§āĻ°āĻžāĻ¸āĻā§āĻāĻŋāĻ āĻĒāĻŖā§āĻ¯
âī¸ Side Effects
Nasopharyngitis, diarrhea, Hypoglycemia (especially when used with sulfonylureas).
âī¸ Dosage & Administration
Immediate Release Tablets
- Maximum Dose: 2.5 mg Linagliptin + 1000 mg Metformin twice daily with meals.
Initial Dosing:
- Not on Metformin: 2.5 mg Linagliptin + 500 mg Metformin twice daily.
- Already on Metformin: 2.5 mg Linagliptin + current Metformin dose twice daily.
Extended Release Tablets
- Maximum Dose: 5 mg Linagliptin + 2000 mg Metformin once daily with meal.
Initial Dosing:
- Not on Metformin: 5 mg/1000 mg once daily with food.
- Already on Metformin: 5 mg Linagliptin + equivalent Metformin once daily.
- Switching from immediate release: Use the same total daily doses.
If using 2.5 mg Linagliptin + 1000 mg Metformin XR, take two tablets together once daily.
âī¸ Patient Counseling Tips
- Avoid alcohol: It increases the risk of low blood sugar.
- Be aware of medication interactions (including OTC meds like aspirin and cold remedies).
- Inform the family on how to respond to hypoglycemia.
- Traveling? Keep prescriptions, ID, and medical history.
- Consider wearing a diabetic ID bracelet or card.
âī¸ Overdose Management
- Supportive care is key.
- Linagliptin is not dialyzable.
- Metformin is dialyzable; lactic acidosis is a major concern.
- Signs of overdose: severe weakness, vomiting, drowsiness, breathing problems.
âī¸ Drug Interactions
- Cationic Drugs (e.g., digoxin, morphine): May interact with Metformin via kidney excretion pathways.
- Carbonic Anhydrase Inhibitors (e.g., topiramate): May increase risk of metabolic acidosis.
- CYP3A4 or P-gp Inducers (e.g., rifampin): May reduce Linagliptinâs effectiveness â avoid combination.
- Drugs Affecting Glycemic Control (e.g., steroids, estrogens, diuretics): May raise blood sugar levels â monitor closely.
âī¸ Contraindications
- Renal impairment (due to Metformin excretion risk).
- Metabolic acidosis (including diabetic ketoacidosis).
- Allergy to Linagliptin or Metformin.
âī¸ Use in Pregnancy & Lactation
- No well-controlled studies in pregnant women.
- Use only if clearly needed.
- Caution advised during breastfeeding.
âī¸ Precautions & Warnings
- Lactic Acidosis risk (rare but serious): Watch for signs like fatigue, muscle pain, and shallow breathing.
- Pancreatitis: Discontinue if suspected.
- Surgery or Contrast Dye Procedures: Temporarily stop Liglimet.
- Vitamin B12 Deficiency: Monitor blood counts annually.
Signs of lactic acidosis:
Abdominal pain, diarrhea
Fatigue, muscle pain
Fast breathing
Drowsiness
Signs of pancreatitis:
Severe stomach pain
Nausea/vomiting
Loss of appetite
Fever or chills
âī¸ Storage Conditions
- Store in a cool, dry place below 30°C, away from moisture and light.
- Keep out of reach of children
â ī¸Disclaimer:
At ePharma, weâre committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.
