Zif-A Tablet 10pcs

✔️ Uses of Zif-A Tablet

Iron, Folic Acid, and Zinc deficiency, Dietary supplement, Pregnanc,y and lactation

✔️ Pharmacology

Ferrous Ascorbate (Iron + Vitamin C):

• Iron is essential for hemoglobin formation and oxygen transport in red blood cells.
• Ascorbic acid (Vitamin C) enhances iron absorption and maintains its bioavailability.

Folic Acid (Vitamin B9):

• Supports red blood cell production and nucleic acid synthesis.
• Prevents neural tube defects in pregnancy.

Zinc:

• Plays a role in over 100 enzymatic processes, DNA synthesis, immune function, and insulin regulation.

✔️ Overdose Effects of Zif-A Tablet

Symptoms:

• Abdominal pain, nausea, vomiting, diarrhea, hypotension, seizures, and coma.
  Action: Seek immediate medical attention in case of overdose.

✔️ Side Effects of Zif-A Tablet

• Common:
  • Gastrointestinal discomfort: abdominal pain, nausea, vomiting, constipation, diarrhea, heartburn.
• Rare/Serious:
  • Allergic reactions (rash, itching, swelling).

✔️ Dosage & Administration of Zif-A Tablet

Adults:

• 1–2 capsules/tablets daily, preferably on an empty stomach for better absorption. If GI irritation occurs, take it with or after meals.

Children (Over 1 Year):

• 1 capsule daily.

Elderly:

• 1 capsule daily or as prescribed by a physician.

✔️ Drug Interactions

• Tetracyclines and Antacids: May reduce iron absorption.
• Chloramphenicol: This may delay the response to iron therapy.
• Levodopa, Methyldopa, Penicillamine: Absorption may be reduced when taken together.
• Quinolones and Tetracyclines: Reduced efficacy due to impaired absorption of both drugs.

Recommendation: Avoid taking these medications within 2 hours of this supplement.

✔️ Contraindications:

• Hypersensitivity to any ingredients.
• Folic acid is contraindicated in untreated cobalamin (Vitamin B12) deficiency, as it may mask symptoms of pernicious anemia.
• Hemolytic anemia or other conditions with increased iron content in the body.

✔️ Pregnancy & Lactation

• Safe during the second and third trimesters of pregnancy.
• Avoid during the first trimester unless there is confirmed evidence of iron deficiency.
• Zinc supplementation is especially recommended during pregnancy and breastfeeding.

✔️ Key Advantages of the Ferrous Ascorbate Complex

1. Improved Iron Utilization:
   • Unlike other iron salts, ferrous ascorbate ensures high bioavailability of iron without dissociating in the GI tract, thus reducing side effects like nausea or constipation.
2. Resistance to Food Inhibitors:
   • Unlike ferrous sulfate, this complex is not significantly affected by phytates or tannins in the diet, allowing consistent absorption even with food.
3. Direct Impact on Erythropoiesis:
   • Ascorbic acid not only aids iron absorption but also has a direct effect on red blood cell production.

✔️ Precautions & Warnings

• Use cautiously in conditions such as:
  • Iron Overload Disorders (e.g., hemochromatosis, hemolytic anemia, red cell aplasia).
  • Renal Failure, where zinc accumulation risk exists.
• Failure to respond to treatment may indicate another cause of anemia and should be investigated.
• Avoid concurrent use with tetracyclines, antacids, or other medications that may interact with iron absorption.

✔️ Storage:

• Store below 30°C, away from light and moisture.
• Keep out of reach of children.