Generic Name: Ferrous Sulfate 150mg+ Folic acid 0.05%+ Zinc Sulfate 61.8mg
Manufacturer/Distributor: Square Pharmaceuticals Ltd.
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Indications of Zif Capsule
Zif Capsule is indicated for the treatment and prophylaxis of iron, folic acid, and zinc deficiency, especially during pregnancy and lactation.
Pharmacology
The mineral iron comes in the form of carbonyl iron. The body needs iron for a variety of processes, most notably the transportation of oxygen in the blood. Iron deficiency and iron deficiency anemia are prevented and treated with carbonyl iron, a dietary supplement.
The synthesis of DNA required for cell replication, the metabolism of amino acids, and the creation of red blood cells are all enhanced by folic acid (compounds necessary for the manufacture of proteins).
Several physiological activities, including the operation of numerous enzymes in the body, depend on zinc. Poor night vision, slow wound healing, poor male sexual development and function, poor appetite (possibly due to a decrease in the sense of taste and smell), a decreased ability to fight infections, diarrhea, dermatitis, and in children, growth retardation are all possible consequences of deficiency.
Dosage & Administration of Zif Capsule
Adult or Elderly: 1 capsule daily. In more severe cases, 2 capsules daily may be required.
Children: Aged over 1 year: 1 capsule daily. The capsule may be opened and the pellets be mixed with soft cool food, but they must not be chewed or as directed by the physician.
Interaction
Levodopa, levothyroxine, methyldopa, quinolone antibiotics, tetracycline antibiotics, and penicillamine are all inhibited by carbonyl iron. Phenobarbital, phenytoin, and primidone plasma concentrations may be lowered as a result of folic acid's interactions with antiepileptic drugs.
Contraindications
Patients with extra iron or those who are hypersensitive to the product's ingredients shouldn't use Zif Capsule.
Side Effects of Zif Capsule
Possible adverse effects include nausea, anorexia, vomiting, discomfort, constipation, and diarrhea. Patients may express concern about their black stools. Pellets of carbonyl iron have been added to the capsules to lessen the possibility of stomach pain. Iron >10% nausea, eructation, diarrhea, and epigastric discomfort. Undefined Vomiting Frequency Hemosiderosis (after long-term administration of huge quantities) (during long-term administration of large amounts), discolored urine, some formulas cause dental stains, Heartburn Vitamin B12 Bronchospasm, Erythema, Malaise, Pruritus, Rash, a little flushing Zinc Nausea/vomiting, stomach irritability, elevated serum levels of alkaline phosphatase, amylase, and lipase that may revert to high levels of normal after 1-2 years of treatment, the decline in neurologic function. Rarely, allergic reactions could happen.
Pregnancy & Lactation
Any medication should be avoided during the first trimester of pregnancy if at all feasible. Iron administration during the first trimester, therefore, necessitates definitive proof of Iron insufficiency. During the duration of the pregnancy, prophylaxis of iron deficiency is warranted if an insufficient diet necessitates supplemental Zinc and Folic acid.
Precautions & Warnings
Patients with iron overload conditions, such as hemochromatosis, hemolytic anemia, or red blood cell aplasia, should be treated with extra caution. Failure to respond to therapy necessitates further examinations to rule out other causes of anemia. Zinc buildup may be a concern in people with renal failure.
Storage Conditions
Store at temperatures below 30°C and away from light and moisture. Keep any medications out of children's reach.
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