5HTP Capsule 6pcs

✔️ Composition of 5HTP Capsule

Each vegetable capsule contains:

• 5-Hydroxytryptophan (from Griffonia simplicifolia): 100 mg
• Powdered valerian extract (from Valeriana officinalis): 100 mg

✔️ 5-HTP is indicated for:

• Anxiety
• Insomnia
• Depression
• Chronic headache
• Fibromyalgia

✔️ Side Effects of 5HTP Capsule

• Drowsiness
• Nausea
• Vomiting
• Stomach pain
• Heartburn
• Diarrhea
• Loss of interest in sex

✔️ Pharmacology

5-Hydroxytryptophan (5-HTP): Converted "in vivo" to serotonin, a neuro-hormonal transmitter released by neurons in the brain, spinal cord, and sympathetic ganglia. It is derived from the seeds of the African plant Griffonia simplicifolia. 5-HTP, an aromatic amino acid naturally produced from L-tryptophan, is extracted commercially from these seeds.

Valerian Extract: Effective in treating mild-to-moderate sleeping disorders without adverse effects on REM sleep or significant hangover effects. Valerian has sedative-hypnotic, anxiolytic, antidepressant, anticonvulsant, and antispasmodic properties.

5-HTP primarily increases serotonin levels within the central nervous system. It has also been shown to raise levels of other neurotransmitters and CNS chemicals, such as melatonin, dopamine, norepinephrine, and beta-endorphin, following oral administration.

Valepotriate in valerian binds to dopamine receptors. Valerenic acid appears to inhibit the enzyme system responsible for GABA catabolism in the central nervous system, thereby increasing GABA concentration and decreasing CNS activity.

Valerian extracts, containing amino acids and valeric acid, bind with the GABA-A receptor in the brain cortex. Valerian extract inhibits GABA uptake and stimulates its release, leading to increased GABA concentration in synaptic clefts. Valerenic acid may inhibit enzymes that break down GABA, thus elevating GABA levels and producing a CNS-depressing effect.

✔️ Dosage & Administration of 5HTP Capsule

Take 1 or 2 vegetable capsules daily, or as directed by a registered physician.

• চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন

✔️ Interaction

• Carbidopa: Concurrent use may increase the risk of developing scleroderma-like illness in susceptible individuals.
• Monoamine Oxidase Inhibitors (MAOIs) & Selective Serotonin Reuptake Inhibitors (SSRIs): Concurrent use may increase the risk of serotonin syndrome (symptoms include hypertension, hyperthermia, myoclonus, and mental status changes). Combining 5-HTP with SSRIs may enhance the risk of serotonergic side effects. Valerian may potentiate the sedative effects of barbiturates, alcohol, and benzodiazepines.

✔️ Contraindications

The World Health Organization (WHO) advises against using valerian for children under 18 year without medical supervision.

✔️ Pregnancy & Lactation

The safety of 5-HTP during pregnancy or lactation has not been established in controlled trials; therefore, it should not be used during pregnancy.

✔️ Storage Conditions

Store in a cool, dry place, away from light and moisture. Keep out of reach of children.