Clobetasol Propionate, the active ingredient in Dermacort 10 Cream, is indicated for the treatment of various dermatoses in adults, the elderly, and children over the age of one year. These conditions include:
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Dermacort 0.05% Topical Cream contains Clobetasol, a topical corticosteroid, used in adults and adolescents (aged 12 years or above) for the treatment of inflammatory skin conditions such as psoriasis, eczema, and dermatitis that have not responded to milder steroid creams or ointments.
Conditions Treated:
Usage Guidelines:
Common Side Effects:
Important Note: Contact your doctor if symptoms worsen or persist.
No interaction found/established
Dermacort 0.05% Topical Cream should be used during pregnancy only if recommended by your doctor. Consult your doctor before using Dermacort 0.05% Topical Cream.
Dermacort 0.05% Topical Cream should be used with caution by breastfeeding women. Consult your doctor before using Dermacort 0.05% Topical Cream.
Dermacort 0.05% Topical Cream is not expected to have any effects on your ability to drive and use machines.
Dermacort 0.05% Topical Cream should be used with caution in patients with kidney disease. Consult your doctor before using Dermacort 0.05% Topical Cream.
Dermacort 0.05% Topical Cream should be used with caution in patients with liver disease. Consult your doctor before using Dermacort 0.05% Topical Cream.
It works by blocking the production of certain chemical messengers that make the skin red, swollen, and itchy.
Common adverse effects include burning and stinging sensations. Less common side effects may include itching, skin atrophy, cracking, and fissuring of the skin. Prolonged use may lead to Cushing syndrome, especially observed in babies and adults.
Clobetasol is used in the treatment of allergic skin conditions.
Clobetasol Propionate exhibits its therapeutic effects by reducing mast cell density, chemotaxis, and eosinophil activation. It also diminishes cytokine production and inhibits arachidonic acid metabolism.
Co-administration with medications inhibiting CYP3A4 (e.g., ritonavir, itraconazole) may decrease corticosteroid metabolism, leading to increased systemic exposure.
Clobetasol Propionate Cream should be used during pregnancy and lactation only if the potential benefit justifies the potential hazards. Caution is advised during breastfeeding, as it is uncertain if the medication is excreted in human milk.
Keep below 30°C, away from light and moisture. Store out of reach of children.
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