Gatison combines an antibiotic with a corticosteroid.
Gatifloxacin: A fluoroquinolone antibiotic that inhibits bacterial DNA gyrase and topoisomerase IV. These enzymes are essential for bacterial DNA replication and cell division. Their inhibition prevents susceptible bacteria from multiplying and can cause bacterial death.
Dexamethasone: A corticosteroid that reduces inflammation by inhibiting inflammatory pathways, including phospholipase A2 activity, and reducing the migration of inflammatory cells. It helps relieve redness, swelling, and other inflammatory symptoms.
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Gatison Eye Drops is a combination ophthalmic medicine containing gatifloxacin 0.3% and dexamethasone phosphate 0.1%. It is used for certain steroid-responsive inflammatory eye conditions associated with bacterial infection or when bacterial infection is a significant concern.
Depending on the ophthalmologist's assessment, it may be prescribed for:
Not all these conditions are suitable for antibiotic-steroid eye drops. An ophthalmologist should determine use.
Gatison is contraindicated in patients with:
Hypersensitivity to gatifloxacin, dexamethasone, or any other ingredient.
Certain untreated viral infections of the eye, including epithelial herpes simplex keratitis.
Fungal infections of ocular structures.
Other contraindications may apply depending on the specific eye condition and product labeling.
The supplied product information recommends instilling 1–2 drops into the conjunctival sac 3–4 times daily. However, the prescribing ophthalmologist must determine the appropriate dose and duration based on the eye condition.
How to apply:
Specific interaction studies for this eye-drop combination may be limited. Inform your doctor about all medicines and eye preparations you use.
The supplied product information identifies potential interactions involving gatifloxacin and products containing aluminum, calcium, magnesium, or zinc, as well as digoxin and probenecid. The clinical significance of interactions from topical ophthalmic use may differ from oral use.
Pregnancy: There are limited controlled safety data for this combination in pregnant women. Use only when the ophthalmologist considers the expected benefit to outweigh potential risks.
Breastfeeding: It is not fully established how much of either ingredient reaches breast milk after topical eye administration. Consult your physician before use.
Store in a cool, dry place away from light, following the manufacturer's instructions.
Keep out of reach of children.
Avoid touching the dropper tip to any surface.
Discard the bottle one month after first opening if specified by the product label.
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At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.