Epinast 0.05% Sterile Ophthalmic Solution

Uses of Epinast 0.05% Sterile Ophthalmic Solution

• Allergic Conjunctivitis

How does Epinast 0.05% Sterile Ophthalmic Solution work?

Epinastine is an antihistaminic medication. It treats allergy symptoms such as itching, swelling, and rashes by blocking the effects of a chemical messenger (histamine) in the body.

Side Effects of Epinast 0.05% Sterile Ophthalmic Solution

Common side effects may include mild burning sensation, folliculitis, hyperemia, pruritus, cold symptoms, and upper respiratory infections.

Quick Suggestions:

• Avoid using this medication if you are allergic to it.
• Remove contact lenses before using the eye drops and wait for 10 minutes after installation before reinserting them.
• Do not use contact lenses if your eyes are inflamed or irritated.
• Inform your doctor about your complete medical and medication history to rule out any potential interactions.
• While Epinast 0.05% Sterile Ophthalmic Solution is an external preparation, consult your doctor if you are pregnant or breastfeeding before using the medication.
• It is safe for use in children older than two years.
• Do not let the dropper's tip touch your eyelids or any other surface, as this can lead to contamination.
• Epinast 0.05% Sterile Ophthalmic Solution is intended for ophthalmic (eye) use only and should be avoided near the ears, nose, and mouth.

Indication

Epinast 0.05% Sterile Ophthalmic Solution is used to treat the signs and symptoms of allergic conditions in the front part of the eye. It is a locally effective antihistamine that works by blocking histamine receptors and stabilizing mast cells, which helps prevent the release of inflammatory substances from blood vessels. Epinastine does not cross the blood-brain barrier, so it is not expected to cause central nervous system side effects.

Pharmacology

Epinastine is a potent local antihistamine that blocks both H1 and H2 histamine receptors. Additionally, it stabilizes mast cells, preventing the release of inflammatory mediators from blood vessels. Importantly, Epinastine does not penetrate the blood-brain barrier, minimizing the likelihood of central nervous system side effects.

Dosage & Administration of Epinast 0.05% Sterile Ophthalmic Solution

The recommended dosage is to instill 1 drop into the affected eye(s) twice daily. Epinast 0.05% Sterile Ophthalmic Solution is not recommended for use in children below 12 years of age. It should be used with caution in children and adolescents aged 12 years and older. 

Interaction

No interactions found/established.

Contraindications

Epinastine should not be used by individuals who are allergic to epinastine or any of the components in the preparation.

Pregnancy & Lactation

Epinastine should only be used during pregnancy if the potential benefits outweigh the potential risks to the fetus. It's unclear whether Epinastine passes into breast milk, so caution is advised when using it while nursing.

Precautions & Warnings

Epinast 0.05% Sterile Ophthalmic Solution is for ophthalmic use only. Patients are advised not to wear contact lenses if their eyes are red.

Storage Conditions

Store Epinast 0.05% Sterile Ophthalmic Solution in a cool, dry place, away from light. It should not be used longer than one month after first opening, and it should be kept out of the reach of children.