Benozol PF is used to manage elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma.
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Benozol PF inhibits carbonic anhydrase (CA), an enzyme found in various tissues, including the eye. By blocking CA activity in the ciliary processes it reduces the formation of bicarbonate ions, leading to decreased sodium and fluid transport. This results in reduced aqueous humor production and lower intraocular pressure (IOP).
Caution is advised in patients taking high-dose salicylates, especially those also taking oral carbonic anhydrase inhibitors, due to the risk of rare interactions.
Hypersensitivity to any component of the formulation.
Pregnancy Category C: Use only if the potential benefit outweighs the risk.
Exercise caution during lactation.
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