Tablet. Manufacturer/Distributor: Square Pharmaceuticals Ltd. Generic Name: Clopidogrel 75 mg
Clopidogrel is indicated for the reduction of atherosclerotic events like myocardial infarction, stroke and vascular death in patients with atherosclerosis documented by recent stroke, recent myocardial infarction or established peripheral arterial disease.
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Acute coronary syndrome (ACS): it is suitable for reducing the occurrence of myocardial infarction (MI) and stroke in patients with non-ST-segment elevation ACS [Unstable angina (AI) / non-ST-segment elevation myocardial infarction (NSTEMI) ] Rate. It is used to reduce the incidence of myocardial infarction and stroke in patients with ST-elevation myocardial infarction (STEMI).
Recent MI, Recent Stroke, or Confirmed Peripheral Artery Disease: For patients with confirmed peripheral artery disease or recent myocardial infarction (MI) or a history of recent stroke, it can reduce the incidence of myocardial infarction and stroke.
Clopidogrel is a prodrug. It inhibits platelet activation and aggregation by irreversibly binding its active metabolites to P2Y12 ADP receptors on platelets. A dose-dependent inhibition of platelet aggregation can be observed 2 hours after a single oral administration. A repeated daily dose of 75 mg inhibited ADP-induced platelet aggregation on the first day, and the inhibition reached a steady state between the 3rd and the 7th day.
Acute coronary syndrome: For patients who need to exert antiplatelet effects within a few hours, start clopidogrel with a single oral loading dose of 300 mg (4 tablets) and then continue to take 75 mg once daily. Starting without a loading dose will delay the onset of antiplatelet effects for several days.
Recent MI, recent stroke, or established peripheral artery disease: 75 mg orally once daily with no loading dose.
Oral with or without food.
Anclog is contraindicated in the following situations: Allergic to any component of the drug or product. Active pathological bleeding, such as a peptic ulcer or intracranial hemorrhage.
There is no adequate and well-controlled study of pregnant women. It should be used during pregnancy only when clearly necessary. It is not known whether clopidogrel is excreted in human milk. The importance of the drug to the mother should be considered and a decision made to stop breastfeeding or discontinue the drug.
Keep below 30°C temperature in a dry place. Protected from light. Do not freeze. Keep out of the reach of children.
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