Purifen 200mg Tablet 10pcs

✔️ Uses of Purifen 200mg Tablet

• Pain Relief

✔️ How to take Purifen 200mg Tablet?

• Purifen 200 is taken with food, preferably with a glass of water.
• The dose and duration will depend on the severity of your condition.
• Continue taking the medicine until your doctor advises stopping.

✔️ Common side effects include:

• Dyspepsia (indigestion)
• Diarrhea
• Fatigue
• Headache
• Nausea
• Vomiting
• Abdominal pain
• Hypersensitivity reactions
• Bleeding and ulcers

✔️ Quick Suggestions:

• Take Purifen 200mg Tablet with food or milk to prevent an upset stomach.
• Follow the prescribed dose and duration.
• Long-term use may lead to serious complications such as stomach bleeding and kidney problems.
• Avoid indigestion remedies (antacids) within two hours of taking Purifen 200mg Tablet.
• Avoid alcohol while taking this medication.
• Inform your doctor if you have a history of heart disease or stroke.
• Regular monitoring of kidney function, liver function, and blood levels may be needed for long-term treatment.

✔️ Indication of Purifen 200mg Tablet

Purifen 200 is a pain-relieving medicine used for the symptomatic treatment of pain and inflammation associated with osteoarthritis, painful menstruation, and other musculoskeletal or dental pain.

✔️ Pharmacology

Dexibuprofen, the active ingredient in Purifen, is the pharmacologically active enantiomer of racemic ibuprofen. It is a non-steroidal anti-inflammatory drug (NSAID) with analgesic action that works by inhibiting prostaglandin synthesis, thereby reducing inflammation and pain.

✔️ Dosage & Administration:

• Dosage: The dosage must be adjusted based on the severity of the condition and the patient’s symptoms.
  • General recommended dosage: 600-900 mg per day, divided into 2-3 doses.
  • Maximum dosage: Up to 1200 mg per day in cases of acute disorders or exacerbations.
  • For dysmenorrhea: 600-900 mg per day, divided into multiple doses.
• Hepatic Impairment: Dose reduction is recommended.
• Renal Impairment: Dose reduction is recommended.

✔️ Interaction

Avoid concomitant use with anticoagulants, other NSAIDs, and salicylates. Increases risk of methotrexate and lithium toxicity.

✔️ Purifen is contraindicated in patients with:

• Hypersensitivity to Dexibuprofen, other NSAIDs, or any component of the product.
• Asthma, bronchospasm, acute rhinitis, urticaria, or edema after using similar drugs (e.g., aspirin or other NSAIDs).
• Active or suspected hemorrhage.
• Crohn's disease or ulcerative colitis.
• Serious heart diseases, impaired kidney function (GFR <30 ml/min), or liver function impairment.

✔️ Pregnancy & Lactation

• Pregnancy: Although no teratogenic effects have been observed in animal studies, Purifen should be avoided during pregnancy due to known effects of NSAIDs on the fetal cardiovascular system.
• Lactation: Dexibuprofen may pass into breast milk in small to negligible amounts. Use with caution while breastfeeding.

✔️ Precautions & Warnings

• Use with caution in patients with bronchial asthma, chronic pulmonary diseases, allergy-prone individuals, and those with hepatic, renal, or cardiac insufficiency.
• Monitor patients with systemic lupus or other autoimmune diseases closely.
• Avoid in patients with active or suspected hemorrhagic conditions, such as gastro-duodenal ulcers, ulcerative colitis, Crohn's disease, and alcoholism.
• Immediate discontinuation is necessary if allergic reactions occur.

✔️ Storage Conditions:

• Store below 30°C.
• Keep away from light and moisture.
• Keep out of the reach of children.