Peratrum 325mg+37.5mg Tablet

✔️ Side Effects:

The following adverse reactions may happen to this therapy: asthenia, fatigue, hot flushes, dizziness, headache, tremor, abdominal pain, constipation, diarrhea, dyspepsia, dry mouth, nausea, vomiting, anorexia, anxiety, confusion, euphoria, insomnia, nervousness, somnolence, pruritus, rash, increased sweating, etc.

✔️ Dosage | Paracetamol + Tramadol Hydrochloride

For the management of moderate to moderately severe pain: The recommended dose is 1 or 2 tablets every 4 to 6 hours as needed for pain relief up to a maximum of 8 tablets per day.

In case of short-term (five days or less) management of acute pain: The recommended dose is 2 tablets every 4 to 6 hours as needed for pain relief up to a maximum of 8 tablets per day.

This tablet can be administered without regard to food.

Pediatric use: The safety and effectiveness of Peratrum preparation have not been studied in the pediatric population.

Geriatric use:  In general, dose selection for an elderly patient should be cautious, reflecting the greater frequency of decreased hepatic, renal, or cardiac function; of concomitant disease and multiple drug therapy.

Use in Renal Disease: Peratrum preparation has not been studied in patients with impaired renal function. In patients with creatinine clearances of less than 30 ml/min, it is recommended that the dosing interval of Peratrum preparation be increased, but not to exceed 2 tablets every 12 hours.

Use in Hepatic Disease: Peratrum preparation has not been studied in patients with impaired hepatic function. The use of Peratrum preparation in patients with hepatic impairment is not recommended.

✔️ Contraindications:

Tramadol & Paracetamol combination tablets should not be administered to patients who have previously demonstrated hypersensitivity to tramadol, paracetamol, any other component of this product, or opioids. This is contraindicated in any situation where opioids are contraindicated.

✔️ Pregnancy & Lactation

Pregnancy Category C. There are no adequate and well-controlled studies in pregnant women. This combination preparation should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. This combination preparation is not recommended for obstetrical preoperative medication or for post-delivery analgesia in nursing mothers because its safety in infants and newborns has not been studied.

✔️ Precautions & Warnings

• Peratrum preparation may impair mental or physical abilities required for the performance of potentially hazardous tasks such as driving a car or operating machinery.
• Peratrum preparation should not be taken with alcohol containing beverages.
• The patient should be instructed not to take Peratrum preparation in combination with other tramadol or paracetamol-containing products, including over-the-counter preparations.
• Peratrum preparation should be used with caution when taking medications such as tranquilizers, hypnotics, or other opiate containing analgesics.

✔️ Storage:

Store in a cool and dry place. Do not freeze. Keep all medicines out of the reach of children.