Zofen 0.5mg 10 Pcs - ePharma
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Zofen 0.5mg 10pcs

Generic: Pizotifen

Type: Tablet

Pack Size: 10 Pcs

Type: Tab. Manufacturer/Distributor: Aristopharma Generic Name: Pizotifen 0.5mg/tablet

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Discount Price: ৳ 30
MRP: ৳ 31.04 3% Off

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✅ Description:

Indications

As prophylactic treatment of migraine.

In appetite loss of somatic or psychogenic origin in underweight patients.

As an adjuvant to treatment of the underlying condition, such as infectious or parasitic diseases (including during convalescence), chronic diarrhea, anorexia nervosa.

Depressive states in the elderly and mood disturbances in the elderly.

 

Pharmacology

Pizotifen works by blocking serotonin and histamine's peripheral activities in raising cranial vascular membrane permeability and plasma kinin transudation, as well as changing pain thresholds in migraines. Pizotifen inhibits serotonin signaling that causes cranial vasoconstriction, as well as serotonin-enhanced platelet activity and aggregation, by inhibiting 5-HT receptors. There is evidence that it also suppresses bradykinin's peripheral activities. Pizotifen alters tonicity and reduces passive distension of extracranial arteries by inhibiting serotonin reuptake by blood platelets. Pizotifen's hunger-stimulating effects could be attributable to the drug's metabolic effects rather than direct stimulation of the appetite center.

 

Dosage and Administration

For migraine: 1.5mg at night or 0.5 mg three times daily, adjusted according to response within the usual range 0.5-3 mg daily, maximum single dose 3 mg, maximum daily dose 4.5 mg.

Appetite loss:

Children: Low starting doses, gradually increasing to a mean maintenance dosage of 0.025mg/kg/day in 2-3 divided doses, or as directed by the physician.

Adults: Starting dose of 0.5 mg/day, gradually increasing to 0.5 mg three times daily.

Mood disturbances in the elderly: A starting of 0.5 mg/day is recommended increasing-preferably in steps of 0.5 mg daily until the optimum level is reached. Doses up to 12 mg/day are well tolerated.

 

Interaction

Pizotifen may augment the central effects of sedatives, hypnotics, antihistamines (including several common cold remedies), and alcohol. The hypotensive impact of adrenergic neuron blockers is counteracted by pizotifen.

 

Contraindications

Hypersensitivity to Pizotifen and children under 2 years of age. Pizotifen should not be administered in the presence of narrow-angle glaucoma or prostate hypertrophy.

 

Side Effects

Antimuscarinic effects- drowsiness, increased appetite, weight gain. Occasionally nausea, dizziness, CNS stimulation, may occur in children.

 

Pregnancy & Lactation

Use in pregnancy: Information about using Pizotifen in pregnancy is limited, although no ill effects have been reported. The drug should therefore only be given during pregnancy if the potential benefit to the mother justifies the potential risk to the fetus.

Use in lactation: The safety of Pizotifen during lactation has not been established, so mothers should avoid taking it when breastfeeding.

 

Precautions & Warnings

Urinary retention, renal impairment, pregnancy, and breastfeeding should be taken into consideration. Drowsiness may affect the performance of the skilled tasks (e.g. driving), the effect of alcohol is enhanced.

Storage Conditions

Keep in a dry place away from light and heat. Keep out of the reach of children.

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Check our pricing section for Zofen 0.5mg 10pcs price in Bangladesh. After Submitting Order, You may receive phone call for verification, price and delivery confirmation. We deliver inside/outside Dhaka (Delivery all over Bangladesh). We offer express/urgent medicine delivery inside Dhaka. Do not forget to check discount/cashback offers if you are eligible to avail any.

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At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.

📦Pricing Information, Availability:
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