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Tezo 200 Antibiotic Tablet 6pcs
Tedizolid, the active form of Tezo, inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit of Gram-positive bacteria. This mechanism is unique, making cross-resistance with non-oxazolidinone antibiotics unlikely.
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✅ Description:
Tezo, an oxazolidinone-class antibacterial, is indicated for treating acute bacterial skin and skin structure infections (ABSSSI) in adults caused by designated susceptible bacteria. Tezo should only be used to treat or prevent infections confirmed or strongly suspected to be caused by these bacteria to help reduce the development of drug-resistant organisms and maintain the efficacy of antibacterial medications.
Use only as prescribed by a registered physician.
✔️ Dosage & Administration of Tezo 200
- ABSSSI Treatment:
- Intravenous: 200 mg once daily for 6 days (1-hour infusion).
- Oral: 200 mg once daily for 6 days.
No dose adjustment is required when switching between oral and intravenous administration. If a dose is missed, it should be taken as soon as possible, provided it is at least 8 hours before the next dose. If less than 8 hours remain, the missed dose should be skipped, and the regular schedule resumed.
Use only as prescribed by a registered physician.
✔️ Common side effects (occurring in >2% of cases) include:
- Nausea
- Headache
- Diarrhea
- Vomiting
- Dizziness
✔️ Interaction
Oral administration of Tezo may increase plasma levels of drugs that are substrates of Breast Cancer Resistance Protein (BCRP). Monitor for adverse effects if coadministration cannot be avoided.
✔️ Contraindications
There are no known contraindications for Tezo.
✔️ Pediatric Use: Tezo 200
Safety and efficacy in patients under 18 years of age have not been established.
✔️ Geriatric Use: Tezo 200
Limited data are available for patients aged 65 and older. No significant differences in pharmacokinetics have been noted compared to younger adults.
✔️ Overdose Effects
In case of overdose, discontinue Tezo and provide general supportive care. Hemodialysis does not effectively remove tedizolid from systemic circulation.
✔️ Pregnancy & Lactation
- Pregnancy: Category C. Limited human data are available. Use during pregnancy only if the potential benefit outweighs the potential risk to the fetus.
- Lactation: Tedizolid has been found in the breast milk of rats, but its presence in human milk is unknown. Use caution when administering to breastfeeding women.
✔️ Precautions & Warnings
- Neutropenia: Tezo's safety and efficacy in patients with neutropenia (neutrophil count <1000 cells/mm³) have not been thoroughly evaluated. Its effectiveness may be reduced in such patients; consider alternative treatments.
- Clostridium difficile-associated diarrhea: Monitor for signs of diarrhea and evaluate if necessary.
✔️ Storage Conditions
Store tablets and injection vials at 20°C to 25°C. Keep out of reach of children.
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