Lomefloxacin is used in the treatment of bacterial infections. It is also used in infections of urinary tract, tonsils, sinus, nose, throat, female genital organs, skin & soft tissues, and lungs (pneumonia).
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Lomeflox 400mg Tablet belongs to the group of antibiotic medicines called fluoroquinolones indicated in the treatment of mild to moderate bacterial infections such as urinary tract infections and bronchitis. Bacterial infections are caused due to the multiplication of harmful bacteria inside or on the body.
Lomeflox 400mg Tablet contains Lomefloxacin, which works by interfering with the activity of topoisomerase IV and DNA gyrase, which are necessary for the transcription and replication of bacterial DNA. Thereby, Lomeflox 400mg Tablet fights bacteria in the body and treats bacterial infection.
In some cases, Lomeflox 400mg Tablet may cause side effects such as diarrhea, nausea, vomiting, drowsiness, and headache. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to the doctor if any of the side effects persist or worsen.
Consult the doctor if you are pregnant or breastfeeding. Lomeflox 400mg Tablet is not recommended for children below 18 years as it might interfere with bone development. Inform your doctor about all the medicines you are taking and your health condition to rule out any unpleasant side effects/interactions.
It is not known if alcohol interacts with Lomeflox 400mg Tablet. Please consult a doctor.
Consult the doctor if you are pregnant. Lomeflox 400mg Tablet should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
Consult the doctor if you are breastfeeding. A decision should be made whether to discontinue nursing or the medicine, considering the importance of the treatment to the mother.
Lomeflox 400mg Tablet may cause dizziness. Be cautious while driving or operating heavy machinery. Avoid activities requiring alertness if you experience dizziness.
Modification of dosage is recommended in patients with kidney dysfunction, So inform your doctor if you have a history of kidney disease.
Limited information was available about using Lomeflox 400mg Tablet in patients with liver disease. Inform your doctor before receiving the Lomeflox 400mg Tablet if you have a history of liver diseases/conditions. Your doctor will prescribe only if the benefits outweigh the risks.
Lomefloxacin is an antibiotic. It works by stopping the action of a bacterial enzyme called DNA-gyrase. This prevents the bacterial cells from dividing and repairing, thereby killing them.
Nausea, Headache, Diarrhea, Insomnia (difficulty in sleeping), Constipation, Dizziness
A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect the body. It can target any body part and multiply very quickly. Generalised symptoms of bacterial infection include fever, chills, and fatigue. Anyone can become infected with a bacterial infection. However, people with a weak immune system or taking immunosuppressive medicines are more prone to bacterial infection.
Lomefloxacin is a difluorinated quinolone derivative that acts as a bacterial gyrase inhibitor, making it effective against both gram-positive and gram-negative bacteria. Its mechanism involves interference with bacterial DNA processes, including replication, transcription, and repair. Specifically, Lomefloxacin targets the A-subunit of the bacterial enzyme gyrase (topoisomerase II), forming a stable complex with the gyrase tetramer (A2B2). This complex impairs the enzyme's function, leading to the rapid death of susceptible bacteria.
Despite its effectiveness, Lomefloxacin has been noted for cross-resistance with other quinolones, but not with other classes of antibiotics. However, there are no clinical studies confirming its efficacy in treating infections caused by chlamydia.
Take Lomeflox 400mg Tablet with or without food. Swallow it as a whole with a full glass of water; do not crush or chew it.
Inform your doctor if you are taking steroids (dexamethasone), anti-diabetic (glipizide), and NSAID (aspirin).
Inform the doctor if you have colitis, CNS disorders, myasthenia gravis (neuromuscular disease), peripheral neuropathy, tendonitis (inflammation of tendons), diabetes, crystalluria (presence of crystals in urine), or kidney problems.
Do not take Lomefloxacin if you are allergic to any of its components.
Lomefloxacin passes through the placenta and is excreted into breast milk in animals, but there are no adequate human studies. It should only be used during pregnancy or lactation if the potential benefits outweigh the risks to the fetus or infant.
Individuals with hypersensitivity to Lomefloxacin, its excipients, or other quinolones should avoid using this medication. Long-term use may also lead to secondary fungal infections or the growth of non-susceptible bacteria.
Store the eye drops in a cool, dry place, protected from light and moisture, and keep them out of reach of children.
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