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Flagyl 400mg Tablet 1 Strip
Metronidazole 400mg
- Bacterial infections
- Parasitic infections
- Post-surgical infection prevention
- Dental and periodontal infections
- Ulcers and skin wounds
- Vaginal and gastrointestinal infections
- Brain abscesses and meningitis
- H. pylori-related ulcers
- Rosacea
- Septicemia and endocarditis
- Bone and joint infections
- Anaerobic bacterial infections
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✅ Description:
Metronidazole is converted in anaerobic cells into active compounds that interact with DNA, disrupting its helical structure. This prevents protein synthesis and ultimately causes cell death in susceptible organisms.
Flagyl 400 is a broad-spectrum antibiotic that combats infections caused by bacteria and parasites. It is commonly prescribed to treat infections affecting the gastrointestinal tract, liver, vagina, brain, heart, lungs, bones, skin, and post-surgical sites. Additionally, it is effective for dental infections, pressure sores, and leg ulcers. It works best when taken with food at regular intervals as prescribed.
Relevant Products / প্রাসঙ্গিক পণ্য
✔️ Dosage & Administration of Flagyl 400
Adults (Oral):
- Amoebiasis: 800 mg 3 times daily for 5–10 days
- Giardiasis: 2 g once daily for 3 days or 500 mg twice daily for 7–10 days
- Trichomoniasis: 2 g as a single dose or 400 mg twice daily for 5–7 days
- Bacterial vaginosis: 2 g once or 400 mg twice daily for 5–7 days
- Anaerobic infections: 800 mg initially, then 400 mg every 8 hours (Max 4 g/day)
- H. pylori: 400 mg twice daily along with other antibiotics and a proton pump inhibitor
Children (Oral):
- Amoebiasis: 100–400 mg depending on age, 3–4 times daily for 5–10 days
- Giardiasis: 500 mg to 1 g daily for 3 days based on age
- Trichomoniasis: 40 mg/kg as a single dose or 15–30 mg/kg/day in divided doses
✔️ Hepatic Impairment:
In severe liver disease, use only one-third of the usual dose once daily.
✔️ Side Effects
- Nausea
- Metallic taste
- Headache
- Dry mouth
- Vomiting, diarrhea, and constipation
- Furred tongue, oral thrush, stomatitis
- Dizziness, drowsiness, insomnia, mood changes
- Tingling or numbness in limbs, seizures (with prolonged use)
- Urethral discomfort, dark urine
- Liver enzyme elevation, jaundice
- Rare: Anaphylaxis, blood cell disorders, antibiotic-associated colitis
✔️ Directions for Use: Flagyl 400
Take the tablets with meals and swallow them whole with water. Do not crush or chew. Maintain consistent timing each day for best results. For suspensions, administer on an empty stomach.
✔️ Drug Interactions
- Disulfiram: Risk of psychosis
- Warfarin: Enhanced anticoagulant effect
- Lithium: Increased risk of toxicity
- 5-Fluorouracil: Reduced clearance, increased toxicity
- Cyclosporine, Busulfan: Increased plasma levels and potential toxicity
- Phenobarbital, Phenytoin: May lower metronidazole levels by enhancing metabolism
✔️ Contraindications:
- Known hypersensitivity to metronidazole or other nitroimidazole derivatives
- Use during first trimester of pregnancy and during lactation is generally not recommended
✔️ Precautions & Warnings
- Caution in patients with neurological disorders or a history of seizures
- Monitor white blood cell counts before and after prolonged use
- Discontinue IV if neurological symptoms arise
- Avoid alcohol during treatment and for at least 48 hours after to prevent adverse reactions
- Prolonged use may result in secondary infections
- Avoid use during the first trimester of pregnancy and while breastfeeding unless necessary
✔️ Storage:
Store in a cool, dry place away from light and moisture. Keep out of reach of children.
Disclaimer:
ePharma sole intention is to ensure that its consumers get proper
information as musch as possible. Although we do not guarantee the
accuracy and the completeness of the information that provided and
here information is for informational purposes only.
The information contained herein should NOT be used as a substitute
for the advice of a qualified physician. This may not cover
everything about particular health conditions,
lab tests, medicines, all possible side effects, drug interactions,
warnings, alerts, etc. Please consult your healthcare professional
and discuss all your queries related to any disease or medicine. We
intend to support, not replace, the doctor-patient relationship.
