✔ 100% Authentic Product
👁️ Currently Viewing 836
Atova EZ 10/10mg Tablet 1 Strip
Lipid-lowering therapy should be part of a comprehensive approach to reducing atherosclerotic vascular disease risk in individuals with hypercholesterolemia. Medication is recommended alongside dietary modifications when non-drug interventions are insufficient.
- Primary Hyperlipidemia: Atova EZ is prescribed to lower total cholesterol (total-C), LDL cholesterol (LDL-C), apolipoprotein B (Apo B), triglycerides (TG), and non-HDL cholesterol, while increasing HDL cholesterol in patients with primary (heterozygous familial and non-familial) hyperlipidemia or mixed hyperlipidemia.
- Homozygous Familial Hypercholesterolemia (HoFH): Used to lower total-C and LDL-C in patients with HoFH, either as an addition to other cholesterol-lowering treatments (e.g., LDL apheresis) or when such options are unavailable.
100% Genuine Products, Guaranteed
Safe & Secure Payments, Always
Fast, Secure & Efficient Delivery
Proper Packaging
Cash on Delivery - All over Bangladesh
Regular Delivery - 8-12 Hours, Dhaka City*- Regular Delivery - 24-48 Hours, All Over Bangladesh*
✅ Description:
- Atorvastatin: Reduces cholesterol by inhibiting HMG-CoA reductase, limiting cholesterol production in the liver, and enhancing LDL receptor activity to facilitate LDL removal from the bloodstream.
- Ezetimibe: Lowers cholesterol by inhibiting its absorption in the small intestine via the Niemann-Pick C1-Like 1 (NPC1L1) transporter. This mechanism reduces hepatic cholesterol stores and increases cholesterol clearance from the blood, complementing statin activity.
Relevant Products / প্রাসঙ্গিক পণ্য
✔️ Dosage & Administration
- General Dosage: 10/10 mg to 80/20 mg daily, taken once a day, with or without food. The starting dose is typically 10/10 mg or 20/10 mg, with adjustments based on lipid levels after 2+ weeks.
- Severe LDL-C Reduction Needs (>55% decrease): Start at 40/10 mg daily.
- Homozygous Familial Hypercholesterolemia: 40/10 mg or 80/10 mg daily, alongside other lipid-lowering treatments where available.
- Patients with Liver Impairment: Not recommended for those with active liver disease or unexplained high liver enzyme levels.
- Patients with Kidney Impairment: No dosage adjustment required, but monitoring for muscle-related side effects is advised.
- Pediatrics: Safety and effectiveness not established.
- Geriatrics: No dosage adjustment needed.
✔️ Common side effects include:
- Muscle issues (rhabdomyolysis, myopathy, myalgia)
- Liver enzyme abnormalities
- Abdominal pain
✔️
Drug Interactions:
- Increased myopathy risk when combined with fibric acid derivatives, high-dose niacin, cyclosporine, or strong CYP3A4 inhibitors (e.g., clarithromycin, HIV protease inhibitors, itraconazole).
- Cyclosporine & Gemfibrozil: Should not be used together with Atova EZ.
- Niacin & Atova EZ: Can increase the risk of muscle-related side effects.
- Warfarin Users: Monitor INR levels if taking alongside Atova EZ.
- Oral Contraceptives: May require dosage adjustments due to changes in hormone levels.
- Colchicine & Atova EZ: Caution advised due to potential muscle-related complications.
✔️ Contraindications:
- Active liver disease or unexplained high liver enzyme levels.
- Hypersensitivity to any ingredient in the formulation.
✔️ Pregnancy & Breastfeeding:
- Pregnancy Category X: Not safe for use in pregnancy, as lipid-lowering drugs do not benefit fetal development. Should be discontinued in pregnant women.
- Lactation: Unknown if atorvastatin is excreted in breast milk; caution is advised.
✔️ Precautions & Warnings:
- Muscle Risks: Myopathy, including rhabdomyolysis, has been linked to atorvastatin, especially when used with colchicine. Discontinue treatment if symptoms occur.
- Liver Monitoring: Liver enzyme levels should be checked before and during treatment. Discontinue if severe liver injury occurs.
- Hormonal Interactions: Use caution when combined with drugs affecting steroid hormone levels (e.g., ketoconazole, spironolactone, cimetidine).
✔️ Storage:
Store below 30°C in a dry place, away from light and out of children's reach
⚠️Disclaimer:
At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.
