Pantoprazole is a proton pump inhibitor (PPI) that suppresses gastric acid secretion by irreversibly binding to the H+/K+ ATPase enzyme system located on gastric parietal cells. This action blocks the final step of acid production and effectively reduces both basal and stimulated gastric acid secretion for more than 24 hours, regardless of the triggering stimulus.
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Pantolok is indicated in conditions where suppression of gastric acid secretion is beneficial, including:
Pantoprazole is classified as US FDA Pregnancy Category B. Although animal studies have not demonstrated harm, adequate controlled studies in pregnant women are lacking. Use during pregnancy only if clearly necessary.
Pantoprazole is excreted into breast milk. A decision should be made whether to discontinue breastfeeding or discontinue the medication, considering the benefit to the mother.
Store in a cool and dry place, protected from light and heat. Keep out of the reach of children.
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