Ace XR 10pcs
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Generic: Caffeine 65 mg + Paracetamol 500 mg

Type: Tablet

Pack Size: 100 Pcs


Urgent Delivery 2 Hours Dhaka City
Free Delivery for Order Tk.999+
Cash on Delivery all over Bangladesh

MRP 20 8% off
18.4
Inclusive of all taxes




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Information about Ace XR 10pcs

Indications of Ace XR

Paracetamol is suitable for fever, common cold and flu, headache, toothache, earache, body pain, myalgia, neuralgia, dysmenorrhea, sprain, colic, back pain, postoperative pain, postpartum pain, inflammatory pain and pain in children after vaccination. It is also suitable for rheumatic pain and osteoarthritis and joint stiffness.

Pharmacology

Paracetamol has analgesic and antipyretic properties, and its anti-inflammatory activity is weak. Paracetamol (acetaminophen) is believed to act mainly on the central nervous system, increasing the pain threshold by inhibiting two isoforms of cyclooxygenase COX1, COX2 and COX3, which are involved in the synthesis of prostaglandin (PG). Paracetamol is a derivative of p-aminophenol, has analgesic and antipyretic effects, and has weak anti-inflammatory activity. Paracetamol is one of the most widely used, safest, and quick-acting analgesics. It is well tolerated and does not have various aspirin side effects.

Dosage & Administration of Ace XR

Tablet:

Adult: 1-2 tablets every 4 to 6 hours up to a maximum of 4 gm (8 tablets) daily.

Children (6-12 years): ½ to 1 tablet 3 to 4 times daily. For long term treatment it is wise not to exceed the dose beyond 2.6 gm/day.

Extended Release Tablet:

Adults & Children over 12 years: Two tablets, swallowed whole, every 6 to 8 hours (maximum of 6 tablets in any 24 hours).The tablet must not be crushed.

 

 

Interaction of Ace XR

Patients taking barbiturates, tricyclic antidepressants, and alcohol may have a reduced ability to metabolize large doses of paracetamol. Alcohol can increase liver toxicity from acetaminophen overdose. Long-term use of anticonvulsants or oral steroid contraceptives may induce liver enzymes and may prevent therapeutic levels of paracetamol from being achieved by increasing metabolism or first-pass clearance.

Contraindications

It is contraindicated in known hypersensitivity to Paracetamol.

Side Effects of Ace XR

The side effects of paracetamol are usually mild, but haematological reactions including thrombocytopenia, leukopenia, pancytopenia, neutropenia, and agranulocytosis have been reported. Occasionally, pancreatitis, skin rash, and other allergic reactions can occur.

Pregnancy & Lactation

U.S. Food and Drug Administration (USFDA) prescribed pregnancy category B. This medicine should be used during pregnancy only if it is clearly needed.

Precautions & Warnings

Paracetamol should be used with caution in patients with renal or liver damage. Patients taking other drugs that affect the liver should use paracetamol with caution.

Storage Conditions: Keep in a dry place away from light and heat. Keep out of the reach of children.

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