Topirva 25 | Antiepileptic Tablet | 10pcs
0 Items
0

Leading Online Pharmacy, of Bangladesh

Home Medicines Epilepsy Topirva 25mg Tablet 10pcs
thumbnail


✔ 100% Authentic Product


Offer

Topirva 25mg Tablet 10pcs

Generic: Topiramate

Type: Tablet

Pack Size: 10 Pcs

Topiramate is used for epilepsy/seizures, Prevention of migraine, and Lennox–Gastaut syndrome.


How to Order

🛒 How to order this item?

Discount Price: ৳ 47.5
MRP: ৳ 50 5% Off

⪼ Save  ৳: 2.5  in this Product


100% Genuine Products, Guaranteed

Safe & Secure Payments, Always

Fast, Secure & Efficient Delivery

Proper Packaging



Cashback offer(Optional):

  • 🏷 Coupon CASH55 ✔️ Get ৳55 back - for Ordering ৳500+
  • 🏷 Coupon CASH120 ✔️ Get ৳120 back - for Ordering ৳1200+
  • 🏷 Coupon CASH200 ✔️ Get ৳200 back - for Ordering ৳2500+
  • 🏷 Coupon CASH300 ✔️ Get ৳300 back - for Ordering ৳3500+
  • 🏷 Coupon CASH400 ✔️ Get ৳400 back - for Ordering ৳4500+
  • 🏷 Coupon CASH500 ✔️ Get ৳500 back - for Ordering ৳5500+
  • 🔹 Delivery charge is applicable for Cashback offer
  • 🔹 Foreign manufacturer products are not applicable for Cashback offer

  • Cash on Delivery - All over Bangladesh
  • Urgent Delivery - 2 Hours Dhaka City

  • ফ্রি ডেলিভারি! - ১৪৯৯ টাকা+ অর্ডারে ঢাকা শহরে ।
  • ফ্রি ডেলিভারি! - ২৯৯৯ টাকা+ অর্ডারে ঢাকার বাহিরে ।

✅ Description:

Topirva 25mg Tablet contains Topiramate, an anticonvulsant. It is used to manage seizure disorders in adults and children (over 6 years) as monotherapy and in children over 2 years as adjunctive therapy. It also treats migraine headaches.

  • Topiramate stabilizes nerve activity by increasing GABA activity (an inhibitory neurotransmitter) and reducing glutamate activity (an excitatory neurotransmitter), thus preventing seizures and migraines.
  • Inform your doctor if you have liver or kidney problems, metabolic acidosis, glaucoma, growth issues, or if you're on a ketogenic diet. Avoid use during pregnancy or breastfeeding without consulting your doctor.

Safety Advices


Alcohol

Avoid alcohol, as it can increase drowsiness and dizziness.


Pregnancy
UNSAFE

Topirva 25mg Tablet is not recommended during pregnancy or breastfeeding unless deemed necessary by your doctor due to potential risks to the baby.


Breastfeeding
CONSULT YOUR DOCTOR

Topirva 25mg Tablet is not recommended during pregnancy or breastfeeding unless deemed necessary by your doctor due to potential risks to the baby.


Driving
CAUTION

Topirva 25mg Tablet can cause drowsiness or dizziness. Avoid driving or operating heavy machinery until you know how the medication affects you.


Kidney
CONSULT YOUR DOCTOR

Topirva 25mg Tablet should be taken with caution in patients having kidney problems, especially kidney stones, or undergoing kidney dialysis. Consult your doctor before taking this medicine.


Liver
CONSULT YOUR DOCTOR

Topirva 25mg Tablet should be taken with caution in patients with liver problems. Consult your doctor before taking this medicine.

Similar Products

✔️ Uses of Topirva 25mg Tablet
  • Treatment of seizures in adults and children (above 6 years of age) alone
  • Treat seizures in adults and children above 2 years of age along with other medicines
  • Prevention of migraine headaches in adults
✔️ Side Effects of Topirva 25mg Tablet
  • Common: Nausea, abdominal pain, dyspepsia, diarrhea, dry mouth, taste disturbance, weight loss, anorexia, paresthesia, headache, fatigue, dizziness, speech disorder, drowsiness, insomnia, impaired memory, anxiety, depression, visual disturbance.
  • Less Common: Suicidal ideation, metabolic acidosis, alopecia.
  • Rare: Leukopenia, thrombocytopenia, serious skin reactions.
✔️ How does Topirva 25mg Tablet work?

It controls seizures or fits by decreasing the abnormal and excessive activity of the nerve cells in the brain.

✔️ Quick Suggestions:
  • It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
  • Keep yourself hydrated by drinking plenty of fluids throughout the day while taking Topiramate. This can reduce the risk of kidney stones.
  • Monitor your weight during treatment with this medicine as it can cause weight gain.
  • Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
  • Do not stop taking the medication suddenly without talking to your doctor as it may increase the seizure frequency.
✔️ Indication of Topirva 25mg Tablet

Epilepsy

  • Monotherapy: For adults and children aged 6 years and above with newly diagnosed epilepsy experiencing generalized tonic-clonic seizures or partial seizures with or without secondary generalization.
  • Adjunctive Therapy: For adults and children over 2 years who are inadequately controlled on conventional first-line antiepileptic drugs for partial seizures with or without secondary generalization, seizures associated with Lennox-Gastaut Syndrome, and primary generalized tonic-clonic seizures.

Migraine

  • Prophylaxis: For adults experiencing three or more migraine attacks per month or frequent attacks that interfere with daily routine. Therapy should be reviewed every six months.
✔️ Pharmacology
  • Seizures: These are caused by abnormal electrical discharges in the brain that lead to reduced alertness, abnormal sensations, and involuntary movements.
  • Mechanism: Topiramate’s exact mechanism is not fully understood but involves actions on sodium channels, GABA receptors, and glutamate receptors, increasing inhibitory GABA activity and reducing excitatory glutamate activity to prevent seizures and migraines. It also blocks voltage-dependent sodium channels and inhibits certain carbonic anhydrase isozymes.
✔️ Dosage & Administration:

Epilepsy Monotherapy:

  • Adults & Children (16+ years): Start at 25 mg nightly for 1 week, increasing by 25-50 mg/day at 1-2 week intervals. Initial target: 100 mg/day, maximum: 400 mg/day.
  • Children (6-16 years): Start at 0.5-1 mg/kg nightly for 1 week, increasing by 0.5-1 mg/kg/day at 1-2 week intervals. Initial target: 3-6 mg/kg/day, maximum: 16 mg/kg/day.

Epilepsy Adjunctive Therapy:

  • Adults & Children (16+ years): Effective dose: 200-400 mg/day in two doses. Maximum: 800 mg/day.
  • Children (2-16 years): Recommended dose: 5-9 mg/kg/day in two doses. Start at 25 mg nightly, increasing by 1-3 mg/kg/day at 1-2 week intervals, maximum: 30 mg/kg/day.

Migraine Prophylaxis:

  • Adults & Children (16+ years): Start at 25 mg nightly for 1 week, increasing by 25 mg/day at 1-week intervals. Target dose: 100 mg/day in two doses. Some benefit at 50 mg/day.
  • Children: Not studied for migraine prevention under 16 years.

Overdose Effects

  • Symptoms: Severe metabolic acidosis.
  • Treatment: Gastric lavage, activated charcoal, supportive care, hemodialysis. Ensure the patient is well hydrated.
✔️ Interaction
  • Antiepileptics: No significant effect on steady-state plasma concentrations except a possible increase in phenytoin levels.
  • CNS Depressants: Use with caution with alcohol and other CNS depressants.
  • Oral Contraceptives: May reduce efficacy, recommend preparations with ≥50 μg estrogen or non-hormonal contraception.
  • Lithium: Monitor lithium levels as systemic exposure increases with higher doses of Topirva.
  • HCTZ & Metformin: May affect serum potassium levels and metformin pharmacokinetics, respectively.
  • Pioglitazone & Glibenclamide: Monitor blood sugar levels.
  • Nephrolithiasis Risk: Avoid use with other nephrolithiasis-inducing agents.
  • Valproic Acid: Can cause hyperammonemia; monitor ammonia levels.
✔️ Contraindications

Hypersensitivity to any components of Topirva.

✔️ Pregnancy & Lactation
  • Pregnancy: Use only if the benefit outweighs the risk.
  • Breastfeeding: Not recommended.
✔️ Precautions & Warnings
  • Gradually withdraw to minimize seizure risk.
  • It can cause CNS-related adverse events (e.g., drowsiness, visual disturbances).
  • Avoid driving or operating machinery if affected.
✔️ Storage Conditions:

Store below 30°C, away from light and moisture. Keep out of reach of children.

Frequently Asked Questions (FAQ)

Yes, it can. Inform your doctor if you experience symptoms such as rapid breathing, fatigue, loss of appetite, or irregular heartbeats. Regular blood tests may be required to monitor your condition.

Do not stop taking the medication without consulting your doctor, even if you feel better, as sudden discontinuation can increase seizure frequency or cause withdrawal symptoms.

Take the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed dose. Do not double the dose to catch up.

Use with caution in children (2-16 years) and the elderly, as they may be more sensitive to side effects.

Common side effects include nausea, abdominal pain, dyspepsia, diarrhea, dry mouth, taste disturbance, weight loss, paresthesia, headache, fatigue, dizziness, speech disorder, drowsiness, and visual disturbances.
Ratings & Reviews

No review

Check our pricing section for Topirva 25mg Tablet 10pcs price in Bangladesh. After Submitting Order, You will receive a phone call for verification, price and delivery confirmation. We deliver inside/outside Dhaka (Delivery all over Bangladesh). We offer express/urgent medicine delivery inside Dhaka. Do not forget to check discount/cashback offers if you are eligible to avail any.

Disclaimer:
ePharma sole intention is to ensure that its consumers get proper information as musch as possible. Although we do not guarantee the accuracy and the completeness of the information that provided and here information is for informational purposes only. The information contained herein should NOT be used as a substitute for the advice of a qualified physician. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your healthcare professional and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Pricing Information, Availability:
ePharma reserves the right to make adjustments to pricing, Products and Service offerings for reasons including, but not limited to, changing market conditions, Product discontinuation, Product unavailability, manufacturer price changes, supplier price changes and errors in advertisements. All orders are subject to Product availability and the availability of Personnel to perform the Services. Therefore, Seller cannot guarantee that it will be able to fulfill Customer’s orders. If Services are being performed on a time and materials basis, any estimates provided by Seller are for planning purposes only.

Hi, there!



Get more features!

Download the app now

  • Pill reminder
  • Prescription & Report
  • Doctor consultation
  • 24/7 helpline