Prucalopride is prescribed for the treatment of chronic idiopathic constipation (CIC)—a condition where bowel movements are infrequent, hard, or incomplete for at least three months, without any identifiable medical cause or medication trigger.
It is usually given to adults when standard laxatives do not provide enough relief.
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Take once daily (or as directed by your doctor), with or without food.
Swallow the tablet whole with a glass of water. Do not crush, chew, or break it.
Continue taking Prucalopride for as long as your doctor advises.
Most of these are mild and improve as your body adjusts. Contact your doctor if they persist.
It is not known if alcohol interacts with Prucalopride. Please consult your doctor if you have any concerns regarding this.
Prucalopride is not recommended during pregnancy. Use a reliable method of contraception while taking Prucalopride. Inform your doctor if you are pregnant, think you are pregnant, or are planning a pregnancy.
Prucalopride might pass into breastmilk. Avoid breastfeeding while taking Prucalopride.
Prucalopride is unlikely to affect your ability to drive. However, sometimes Prucalopride might cause dizziness and tiredness, so drive only if you are alert.
Please consult your doctor if you have kidney impairment/kidney disease.
Please consult your doctor if you have liver impairment/liver disease.
Drug–drug: May interact with some medicines such as diphenhydramine (an antihistamine).
Drug–food: No known interactions with food.
Drug–disease: Avoid in patients with serious bowel conditions, dialysis, or mood disorders unless advised by a doctor.
Do not take Prucalopride if you:
⚠️ Not recommended if you are pregnant, breastfeeding, or under 18 years old.
⚠️ May cause dizziness or tiredness—drive or operate machinery only if you feel alert.
Store in a cool, dry place, away from direct sunlight.
Keep out of reach of children.
⚠️Disclaimer:
At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.