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Religox 120 Tablet | Box
Religox is indicated for the management of adult patients with advanced prostate cancer.
Discount Price: ৳ 2,375
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ফ্রি ডেলিভারিঃ - ১৪৯৯ টাকা+ অর্ডারে, ঢাকা
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100% Genuine Products, Guaranteed
Safe & Secure Payments, Always
Fast, Secure & Efficient Delivery
Proper Packaging
- Cash on Delivery - All over Bangladesh
- Regular Delivery: 24-48 Hours, Dhaka City* Charge Tk.39-59
- Regular Delivery: 48-96 Hours, Other Cities* Charge Tk.99-125
- ফ্রি ডেলিভারিঃ - ১৪৯৯ টাকা+ অর্ডারে, ঢাকা
শহরে
- ফ্রি ডেলিভারিঃ - ৪৯৯৯ টাকা+ অর্ডারে, ঢাকার
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✅ Description:
Relugolix is a non-peptide, small-molecule GnRH receptor antagonist. It binds competitively to pituitary GnRH receptors, thereby reducing the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This results in suppression of testosterone production, which is essential in controlling prostate cancer progression.
- Absorption: Oral bioavailability ~12%; Tmax ~2.25 hours.
- Food effect: High-fat meals do not significantly alter pharmacokinetics.
- Distribution: Plasma protein binding 68–71% (mainly to albumin).
- Metabolism: Primarily via CYP3A, minor by CYP2C8.
- Elimination: Effective half-life ~25 hours; terminal half-life ~61 hours.
- Excretion: ~81% via feces (4.2% unchanged), ~4.1% via urine (2.2% unchanged).
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✔️ Side Effects | Religox 120
Common (≥10%):
- Hot flushes
- Increased blood glucose & triglycerides
- Musculoskeletal pain
- Decreased hemoglobin
- Elevated liver enzymes (ALT, AST)
- Fatigue, constipation, diarrhea
Less common / Rare:
- QT prolongation, dizziness, palpitations, fainting, chest pain
- Weight gain, reduced libido, erectile dysfunction
✔️ Dosage & Administration
Loading Dose: 360 mg orally on Day 1.
Maintenance Dose: 120 mg once daily, taken at the same time each day (with or without food).
Missed Dose:
- If remembered within 12 hours → take immediately.
- If more than 12 hours late → skip the missed dose, continue with next scheduled dose.
- If therapy is interrupted for >7 days → restart with a 360 mg loading dose, then resume 120 mg daily.
Pediatric use: Not established.
Geriatric use: No clinically significant difference observed compared to younger patients.
✔️ Drug Interactions
P-gp inhibitors: Avoid co-administration. If necessary, take Religox first, maintain a 6-hour gap, and monitor closely.
Strong CYP3A inducers (combined with P-gp): Avoid. If unavoidable, increase dose to 240 mg once daily.
✔️ Pregnancy & Lactation
Not indicated for use in women.
Safety and efficacy in pregnancy and lactation have not been established.
✔️ Precautions & Warnings
QT prolongation: Monitor in patients at risk or on QT-prolonging drugs.
Embryo-fetal toxicity: May cause fetal harm; advise contraception for men with female partners of reproductive potential.
Fertility: Relugolix may impair male fertility.
✔️ Storage:
Store in a cool, dry place, protected from light and moisture.
Keep out of reach of children.
⚠️Disclaimer:
At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.
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