Montelukast is used to prevent sneezing and runny nose due to allergies.
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Asthma is a chronic lung disease that causes inflammation and narrowing of the airways, making it difficult to breathe. It affects millions of Americans, leading to frequent emergency room visits if left untreated. Symptoms include coughing, wheezing, shortness of breath, chest tightness, and trouble sleeping. Asthma attacks occur when the airways tighten and become inflamed, leading to severe breathing difficulties and other symptoms like rapid breathing, chest pain, and anxiety. Triggers for asthma attacks include infections, allergens, irritants, exercise, weather changes, and certain medications. Treatment involves various medications, including inhalers and oral medications, to control inflammation and relieve symptoms. Managing asthma involves avoiding triggers, taking medications as prescribed, and having an asthma action plan in place for emergencies. It's essential to maintain a healthy lifestyle and follow medical advice to manage asthma effectively.
Avoid drinking alcohol while taking Monocast 10mg Tablet as it can worsen your side effects like drowsiness.
Monocast 10mg Tablet should be used in pregnant women only if it is considered necessary by the physician. Your doctor will prescribe you Monocast 10 after evaluating the risks and benefits of the therapy.
It is not known whether Monocast 10mg Tablet can pass through breast milk. Therefore, it should be used in breastfeeding women only if considered necessary by the physician.
Monocast 10mg Tablet usually does not affect your ability to drive or operate any machinery. However, do not drive or handle any heavy tools or machines if you feel dizzy or drowsy after taking Monocast 10mg Tablet.
Monocast 10mg Tablet should be used with caution in patients with liver diseases. Let your doctor know if you have any history of liver diseases. Your doctor will weigh the benefits and potential risks before prescribing Monocast.
Monocast 10mg Tablet should be used with caution in patients with kidney diseases. Let your doctor know if you have any history of kidney diseases. Your doctor will weigh the benefits and potential risks before prescribing Monocast 10mg Tablet.
Asthma, Seasonal allergies
Monocast 10 mg selectively and actively inhibits the CysLT1 receptor, preventing cysteinyl leukotrienes from causing airway edema, smooth muscle contraction, and inflammatory changes associated with asthma and allergic rhinitis.
Common side effects include:
Uncommon side effects include:
Rare side effects include:
Monocast 10 mg is indicated for:
Monocast 10 mg operates by inhibiting the cysteinyl leukotriene receptor (CysLT1). The metabolism of arachidonic acid produces cysteinyl leukotrienes (LTC4, LTD4, and LTE4), which are released from cells like mast cells and eosinophils. These leukotrienes bind to receptors located in the human airway. Monocast 10 mg specifically targets and blocks these receptors without any agonist activity, thereby inhibiting the physiological effects of LTD4.
Adults and Adolescents (15 years and older) with Asthma or Seasonal Allergic Rhinitis:
Pediatric Patients with Asthma or Seasonal Allergic Rhinitis:
Special Populations:
Monocast 10 mg can be used with other common asthma treatments without increasing the risk of adverse effects. Studies show no significant interaction with drugs like theophylline, prednisone, prednisolone, oral contraceptives, terfenadine, digoxin, and warfarin. Even though detailed interaction studies weren't conducted, no harmful interactions were observed when used with thyroid hormones, hypnotics, benzodiazepines, NSAIDs, and decongestants. Phenobarbital reduced the drug’s AUC by about 40%, but no dosage adjustment is recommended. Clinical monitoring is advised when used with potent cytochrome P450 enzyme inducers like phenobarbital or rifampin.
Patients with hypersensitivity to any ingredient in Monocast 10 mg should not use it.
Classified as pregnancy category B. While animal studies show the drug crosses the placenta, there are no well-controlled studies in pregnant humans. Some evidence suggests secretion in breast milk, but the implications are unclear. Caution is advised before using during pregnancy or nursing.
Store below 30°C in a cool, dry place, away from light and moisture. Keep out of reach of children.
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