Sensimet 1mg Tablet

Uses of Sensimet 1mg Tablet

How does Sensimet 1mg Tablet work?

Sensimet 1mg Tablet is a medication that contains Rosiglitazone and Metformin, a member of the thiazolidinedione class of drugs. It is prescribed to individuals with type 2 diabetes to help regulate their blood sugar levels. This is achieved by enhancing the body's ability to effectively utilize the insulin it naturally produces. To effectively manage blood sugar levels, Sensimet 1mg Tablet should be used in conjunction with dietary management and regular exercise. Metformin reduces hepatic glucose production, decreases intestinal glucose absorption, and increases peripheral glucose uptake.

Side Effects of Sensimet 1mg Tablet

Common adverse events include upper respiratory tract infection, headache, diarrhea, and nausea.

Quick Suggestions:

• To reduce the risk of having an upset stomach, it's advisable to take Sensimet 1mg Tablet with food. This can help minimize any gastrointestinal discomfort that may occur as a side effect.
• Compared to some other diabetes medicines, Sensimet 1mg Tablet is associated with a lower risk of weight gain and low blood sugar (hypoglycemia). However, it's essential to monitor your blood sugar levels regularly and follow your doctor's instructions to maintain stable glucose levels.
• If you are scheduled to undergo surgery under general anesthesia, it's crucial to inform your doctor about your diabetes treatment. They can provide guidance on managing your blood sugar levels before, during, and after the surgery to ensure your safety and well-being.
• Lactic acidosis is a rare but serious condition that may occur with Sensimet 1mg Tablet. If you experience symptoms such as deep or rapid breathing, persistent nausea, vomiting, and stomach pain, contact your doctor immediately. Lactic acidosis is characterized by an excess of lactic acid in the blood and requires prompt medical attention.

Indication

Sensimet is used alongside diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus who are already on a combination of Rosiglitazone and Metformin or those not adequately controlled on Metformin alone.

Pharmacology

Sensimet combines two antidiabetic agents, Rosiglitazone and Metformin, with different mechanisms of action. Rosiglitazone enhances peripheral glucose utilization, while Metformin reduces hepatic glucose production and increases peripheral glucose uptake.

Dosage & Administration of Sensimet 1mg Tablet

The dose of Sensimet depends on the patient's current doses of Rosiglitazone and Metformin. It should be administered with meals and titrated based on effectiveness and tolerability.

Interaction

Sensimet may interact with drugs affecting CYP2C8 enzymes and cationic drugs, necessitating dose adjustments and monitoring.

Contraindications

Sensimet is contraindicated in patients with renal disease, congestive heart failure, hypersensitivity to its components, or metabolic acidosis. It should also be temporarily discontinued before radiologic studies involving intravascular contrast materials.

Pregnancy & Lactation

It is generally recommended to avoid Sensimet® during pregnancy, and it should not be used while nursing.

Pediatric Use:

Safety and effectiveness in pediatric patients have not been established.

Geriatric Use:

Caution is advised in elderly patients, and renal function should be monitored regularly.

Precautions & Warnings

During stress or other medical conditions, temporary loss of glycemic control may occur, requiring insulin administration. Caution is needed in patients with edema.

Lactic acidosis is a rare but serious complication of Metformin; elderly patients, those with reduced renal function, and those with certain medical conditions are at higher risk.

Storage Conditions

Store Sensimet in a cool, dry place, protected from light and moisture.