Empaglif-M 10/1000 XR Tablet

✔️ Uses of Empaglif-M XR 10/1000

• Management of type 2 diabetes mellitus in adults
• Helps improve blood glucose control when combined with diet and exercise
• May provide cardiovascular benefits in certain adults with type 2 diabetes and established cardiovascular disease, as determined by the treating physician

✔️ Side Effects of Empaglif-M XR 10/1000

Common side effects may include:

• Increased urination
• Increased thirst
• Nausea
• Vomiting
• Diarrhoea
• Abdominal discomfort or pain
• Headache
• Dizziness
• Fatigue
• Dry mouth
• Weight loss

Serious adverse effects may include:

• Diabetic ketoacidosis (DKA)
• Lactic acidosis
• Dehydration
• Urinary tract infections
• Genital fungal infections
• Low blood sugar, particularly when used with insulin or insulin-releasing medicines
• Severe allergic reactions

✔️ Empaglif-M XR 10/1000 may interact with several medicines, including:

• Insulin and sulfonylureas: May increase the risk of hypoglycemia.
• Other glucose-lowering medicines: Blood glucose should be monitored when multiple antidiabetic medicines are combined.
• Diuretics: May increase urination and the risk of dehydration or low blood pressure.
• ACE inhibitors and ARBs: May contribute to lower blood pressure, particularly when combined with volume depletion.
• Corticosteroids: May increase blood glucose levels and reduce diabetic control.
• Beta-blockers: May mask some symptoms of hypoglycemia.
• Medicines affecting kidney function: May increase the risk associated with metformin accumulation, depending on the medicine and the patient's renal status.
• Contrast agents used for certain imaging procedures: Metformin may need to be temporarily withheld in selected patients because of the risk of kidney-related complications and lactic acidosis.

✔️ This medicine should not be used in patients with:

• Type 1 diabetes mellitus
• Diabetic ketoacidosis
• Severe renal impairment or conditions in which metformin is contraindicated
• Known hypersensitivity to empagliflozin, metformin, or any component of the formulation
• Current or previous lactic acidosis associated with metformin

✔️ Pregnancy and Lactation

Empagliflozin is generally not recommended during pregnancy, particularly during the second and third trimesters, because of potential risks to the developing fetus. If pregnancy occurs during treatment, consult your doctor promptly.

Empagliflozin is not generally recommended while breastfeeding because it is unknown whether exposure to the medicine could affect the nursing infant. Metformin is also present in breast milk, so the overall benefits and risks should be discussed with a healthcare professional.

✔️ Precautions

Before starting treatment, tell your doctor if you have kidney or liver disease, a history of recurrent urinary or genital infections, dehydration, heart problems, or a history of lactic acidosis.

Adequate fluid intake is important because empagliflozin can increase urination and may contribute to volume depletion. Blood glucose and kidney function should be monitored as recommended.

The medicine may need to be temporarily discontinued during certain situations, including significant dehydration, serious acute illness, or around some surgical procedures, according to your doctor's instructions.

✔️ Storage:

Store Empaglif-M XR 10/1000 below 30°C, away from direct light and moisture. Keep the medicine in its original packaging and out of the reach of children. Do not use it after the expiry date.