Precodil 5 Oral Solution

Uses of Precodil 5 Oral Solution

• Treatment of Inflammatory conditions
• Treatment of Autoimmune conditions
• Treatment of Severe allergic reactions
• Treatment of Allergic conditions
• Treatment of Rheumatic disorder
• Treatment of Skin disorders
• Treatment of Eye disorders
• Treatment of Nephrotic syndrome

How Precodil 5 Oral Solution works

Precodil 5 Oral Solution is a steroid that works by blocking the production of certain chemical messengers in the body that cause inflammation (redness and swelling) and allergies.

How to use Precodil 5 Oral Solution

Follow your doctor's instructions for this medication's dosage and length. Before using, read the leaflet for instructions. Take it by mouth after measuring it with a measuring cup. Shake firmly before using. Omnacortil Oral Solution should be consumed alongside meals.

Side effects of Precodil 5 Oral Solution

• Behavioral changes
• Edema (swelling)
• Glucose intolerance
• Increased appetite
• Mood changes
• High blood pressure
• Weight gain

Quick Suggestions:

• Giving Precodil 5 Oral Solution with meals is preferred because doing so on an empty stomach might cause acid reflux and stomach acidity.
• Never provide this medication more frequently or for longer than recommended by your doctor.
• There may be an increased risk of new infections in your kid.
• Additionally, in rare circumstances, previous infections may reactivate. If you see any infection-related symptoms in your kid, such as fever, coughing, vomiting, or diarrhea, let the doctor know.
• While your kid is taking Precodil 5 Oral Solution, postpone vaccinations since they could not effective. After speaking with a doctor, the vaccination can be administered as soon as your kid feels better.
  Avoid stopping your medication suddenly. Ask your doctor for advice on how to gradually reduce the dosage because a steroid withdrawal syndrome might develop from an abrupt reduction.
• Always with your child's doctor before administering any additional drugs, including ones that don't require a prescription. (over-the-counter medicines).

Indications of Precodil 5 Oral Solution

Rheumatic Disorders: Psoriatic arthritis, rheumatoid arthritis, juvenile rheumatoid arthritis, ankylosing spondylitis, acute and subacute bursitis, acute nonspecific tenosynovitis, acute gouty arthritis, post-traumatic osteoarthritis.

Dermatologic Diseases: Pemphigus, bullous dermatitis herpetiformis, severe erythema multiforme, exfoliative dermatitis, mycosis fungicides, severe psoriasis.

Allergic States: Seasonal or perennial allergic rhinitis, bronchial asthma, contact dermatitis, atopic dermatitis, serum sickness, drug hypersensitivity reactions.

Respiratory Diseases: Symptomatic sarcoidosis, berylliosis, fulminating, aspiration pneumonitis.

Hematologic Disorders: Idiopathic thrombocytopenic purpura, secondary thrombocytopenia, acquired (autoimmune) hemolytic anemia, erythroblastopenia (RBC anemia).

Endocrine Disorders: Primary or secondary adrenocortical insufficiency, congenital adrenal hyperplasia, nonsuppurative thyroiditis, hypercalcemia associated with cancer.

Edematous States: To induce a diuresis or remission of proteinuria in the nephrotic syndrome, without uremia, of the idiopathic type or that due to lupus erythematosus.

Gastrointestinal Diseases: Ulcerative colitis, regional enteritis.

Pharmacology

Prednisolone is predominantly an adrenocortical glucocorticoid. The Phospholipase A2 enzyme, which produces a variety of inflammatory mediators including leukotrienes, SRS-A, prostaglandins, and others, is directly inhibited by prednisolone. Prednisolone is quickly and completely absorbed from the GI system after oral therapy. Prednisolone is eliminated from the body with a half-life of 2 to 4 hours and is 70–90% protein-bound in plasma. Urine is used to removing it after being mostly digested in the liver.

Dosage & Administration of Precodil 5 Oral Solution

Adult-

Anti-inflammatory: 5 to 60 mg per day in divided doses 1 to 4 times/day.

Acute Asthma: 40-60 mg/day PO in single daily dose or divided q12 hr for 3-10 days.
Nephrotic Syndrome:

• Initial: 2 mg/kg/day (maximum 80 mg/day) in divided doses 3 to 4 times/day until urine is protein-free for 3 consecutive days (maximum: 28 days); followed by 1 to 1.5 mg/kg/dose given every other day for 4 weeks.
• Maintenance dose: 0.5 to 1 mg/kg/ dose given every other day for 3 to 6 months.

Allergic Conditions:

• Day 1: 10 mg PO before breakfast, 5 mg after lunch and after dinner, and 10 mg at bedtime.
• Day 2: 5 mg PO before breakfast, after lunch, and after dinner, and 10 mg at bedtime.
• Day 3: 5 mg PO before breakfast, after lunch, after dinner, and at bedtime.
• Day 4: 5 mg PO before breakfast, after lunch, and at bedtime.
• Day 5: 5 mg PO before breakfast and at bedtime.
• Day 6: 5 mg PO before breakfast.

Pediatric-
 

Anti-inflammatory: 0.05 to 2 mg/kg/day divided 1 to 4 times/day.

Immunosuppression: 0.05 to 2 mg/kg/day divided 1 to 4 times/day.

Asthma:

• 1 year: Acute: 10 mg orally every 12 hours. Maintenance: 10 mg orally every other day.
• 1 to 4 years: Acute: 20 mg orally every 12 hours. Maintenance: 20 mg orally every other day.
• 5 to 12 years: Acute: 30 mg orally every 12 hours. Maintenance: 30 mg orally every other day.
• 12 years: Acute: 40 mg orally every 12 hours. Maintenance: 40 mg orally every other day.

Pregnancy & Lactation

This medicine is not recommended for use during pregnancy unless considered essential by your doctor. It should only be used if the expected benefit to the mother is greater than any possible risk to the fetus. Corticosteroids appear in breast milk and could suppress growth, interfere with endogenous corticosteroid production or cause other unwanted effects.

Precautions & Warnings

• Long-term use of Prednisolone can cause Cushing’s habitus, hyperglycemia, muscular weakness, increased susceptibility to infection, delayed wound healing, and psychiatric disturbances.
• Precaution has to be taken in diabetes, hypertension, Psychological disturbances, osteoporosis, post-menopausal women, pregnancy, and in chronic nephritis.

Storage Conditions

Store in a cool and dry place, protected from light. Keep out of the reach of the children.