Generic Name: Prednisolone 5mg
Manufacturer: Incepta Pharmaceuticals Ltd.
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Indications of Cortan 5
Pharmacology
Prednisolone is a synthetic adrenocortical drug that functions similarly to glucocorticoids. The Phospholipase A2 enzyme, which produces inflammatory mediators like leukotrienes, SRS-A, and prostaglandins, is inhibited by prednisolone. Prednisolone is quickly and completely absorbed from the GI tract after oral ingestion. Prednisolone has a half-life of 2 to 4 hours before it is excreted and is 70–90% protein-bound in the plasma. The liver is where it is primarily processed, and urine is where it is eliminated.
Dosage and Administration
Adult-
Allergic Conditions:
Nephrotic Syndrome:
Anti-inflammatory:
Acute Asthma:
Pediatric-
Asthma:
Anti-inflammatory:
Immunosuppression:
Interaction of Cortan 5
Aminoglutethimide, Antacids, Barbiturates, Carbamazepine, Griseofulvin, Mitotane, Phenylbutazone, Phenytoin, Primidone, and Rifampin all decrease the effectiveness of prednisolone. The amount of potassium in the blood is decreased by prednisolone. If hypokalemia occurs, digitalis may cause cardiac arrhythmias. Care must be taken when administering vaccinations.
Contraindications
Unless specific anti-infective therapy is used, systemic infections can occur. Intolerance to any ingredient Herpes simplex ocular because of potential perforation
Side Effects of Cortan 5
Increased hunger, indigestion, agitation, and restlessness are all common adverse effects. Darkening or lightening of skin color, dizziness or lightheadedness, flushing of the face or cheeks, hiccups, increased sweating, and the impression of spinning is less common or rare adverse effects.
Pregnancy & Lactation
This medicine is not recommended for use during pregnancy unless considered essential by your doctor. It should only be used if the expected benefit to the mother is greater than any possible risk to the fetus. Corticosteroids appear in breast milk and could suppress growth, interfere with endogenous corticosteroid production or cause other unwanted effects.
Precautions & Warnings
Vigilance is necessary for those who have diabetes, hypertension, psychological issues, osteoporosis, postmenopausal women, pregnancy, and chronic nephritis. Long-term Prednisolone use may result in Cushing's syndrome, hyperglycemia, muscle weakness, heightened susceptibility to infection, sluggish wound healing, and psychological disorders.
Storage Conditions
Store in a cool and dry place, protected from light. Keep out of the reach of the children.
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