Arpolax 10pcs - ePharma
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Arpolax 10pcs

Generic: Citalopram Hydrobromide

Type: Tablet

Pack Size: 10 Pcs

Tablet, Generic Name: Citalopram Hydrobromide, Manufacturer: Incepta Pharmaceuticals Ltd.


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Discount Price: ৳ 74.4
MRP: ৳ 80 7% Off

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Description:

Indications of Arpolax 20 Tablet

This preparation is indicated for: Treatment and stand-by emergency treatment of adults, children, and infants with acute, uncomplicated infection due to Plasmodium falciparum or mixed infections including P. falciparum. Because Artemether and Lumefantrine are effective against both drug-sensitive and drug resistant P. falciparum. This preparation is also recommended for malaria infections acquired in areas where the parasites may be resistant to other antimalarials. Stand-by emergency treatment: Most tourists and business travelers, considered to be non-immune, will be able to obtain prompt medical attention if malaria is suspected. However, a minority at risk of infection may be unable to obtain such care within 24 hours of the onset of symptoms, particularly if they are in an isolated location far from medical services. In such cases, prescribers are advised to issue Artemether and Lumefantrine to be carried by the traveler for self-administration (stand-by emergency treatment). Consideration should be given to official guidance regarding the appropriate use of anti-malarial agents.

Pharmacology of Arpolax 20 Tablet

This preparation contains a fixed ratio of 1:6 parts of Artemether and Lumefantrine respectively. Artemether is a derivative of the naturally occurring substance Artemisinin. Lumefantrine is a synthetic racemic fluorine mixture belonging to the aryl amino alcohol family like other antimalarials (e.g. Quinine, mefloquine, halofantrine). Both components act in the food vacuoles of malarial parasites, where they are thought to interfere with the conversion of haem, a toxic intermediate formed during hemoglobin breakdown, to the non-toxic hemozoin (a malaria pigment). Lumefantrine is thought to interfere with the polymerization process, while Artemether generates reactive metabolites as a result of interaction between the peroxide bridge and haem iron. Both Artemether and Lumefantrine have a secondary action involving the inhibition of nucleic acid-protein synthesis within the malarial parasites. This tablet did not induce resistance. This tablet is active against blood stages of Plasmodium vivax, but it is not active against hypnozoites. Therefore, sequential treatment with primaquine should be used to achieve hypnozoite eradication.

Dosage & Administration of Arpolax 20 Tablet

Patients with acute malaria are frequently averse to food. The dose should be taken with high-fat food or drinks such as milk. In the event of vomiting within 1 hour of administration a repeat dose should be taken.

Adults and children weighing 35 kg and above: A standard 3 days treatment schedule with a total of 6 doses is recommended dosage is 4 tablets as a single dose at the time of initial diagnosis, again 4 tablets after eight hours, and then 4 tablets twice daily (morning and evening) on each of the following two days (Total course comprises 24 tablets).

5 to <15 kg body weight: 1 tablet at the time of initial diagnosis, 1 tablet again after 8 hours, and then 1 tablet twice daily (morning and evening) on each of the following two days (Total course comprises 6 tablets).

15 to <25 kg body weight: 2 tablets as a single dose at the time of initial diagnosis, 2 tablets again after 8 hours, and then 2 tablets twice daily (morning and evening) on each of the following two days (Total course comprises 12 tablets).

25 to <35 kg body weight: 3 tablets as a single dose at the time of initial diagnosis, 3 tablets again after 8 hours, and then 3 tablets twice daily (morning and evening) on each of the following two days (Total courses comprises 18 tablets).

Interaction of Arpolax 20 Tablet

No such result is available.

Contraindications

Hypersensitivity to any of the ingredients or excipients; Patients with severe malaria according to WHO definition; First trimester of pregnancy; Patients with a family history of congenital prolongation of the QTc interval or sudden death or with any other clinical condition known to prolong the QTc interval such as patients with a history of symptomatic cardiac arrhythmias with clinically relevant bradycardia or with severe cardiac disease; Patients with known disturbance of electrolyte balance e.g. hypokalaemia or hypomagnesemia; Patients taking any drug which is metabolized by the cytochrome enzyme CYP2D6 (e.g. flecainide, metoprolol, imipramine, amitriptyline, clomipramine).

Side Effects of Arpolax 20 Tablet

It is generally very well tolerated by children and adults, with the most adverse effects of mild to moderate severity and duration. Hypersensitivity, headache, dizziness, sleep disorder, somnolence, involuntary muscle contractions, paraesthesia, hypoesthesia, abnormal gait, ataxia, palpitation, cough, abdominal pain, anorexia, diarrhea, vomiting, nausea, pruritus, rash, arthralgia, myalgia, asthenia, fatigue.

Pregnancy & Lactation

Use in pregnancy & lactation is contraindicated; especially in the first trimester of pregnancy. Breastfeeding women should not take this preparation. Due to the long elimination half-life of Lumefantrine (4-6 days), it is recommended that breastfeeding should not resume before day 28 unless the potential benefits to the mother and child outweigh the risk of treatment.

Precautions & Warnings

This has not been evaluated for prophylaxis and is therefore not indicated. This is also not evaluated for the treatment of cerebral malaria or other severe manifestations of severe malaria including pulmonary edema or renal failure.

Storage Conditions

Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.

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Check our pricing section for Arpolax 10pcs price in Bangladesh. After Submitting Order, You will receive a phone call for verification, price and delivery confirmation. We deliver inside/outside Dhaka (Delivery all over Bangladesh). We offer express/urgent medicine delivery inside Dhaka. Do not forget to check discount/cashback offers if you are eligible to avail any.

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ePharma sole intention is to ensure that its consumers get proper information as musch as possible. Although we do not guarantee the accuracy and the completeness of the information that provided and here information is for informational purposes only. The information contained herein should NOT be used as a substitute for the advice of a qualified physician. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your healthcare professional and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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