Amlodipine 5mg + Atenolol 25mg Tablet
- Hypertension is not controlled by monotherapy.
- Angina pectoris and hypertension co-existing diseases.
- Post myocardial infarction (MI) patients.
- Refractory angina pectoris where nitrate therapy has failed.
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Description:
- Oral treatment for chronic stable angina and hypertension.
- Additive effect with catecholamine-depleting drugs. Monitor for hypotension and bradycardia.
- Excessive BP fall is possible in the elderly. Caution in various conditions.
- Atenolol is cardioselective, and Amlodipine is a calcium-channel blocker, resulting in additive antihypertensive action.
- Avoid untreated phaeochromocytoma.
- Caution in essential hypertension, angina, post-MI, and refractory angina patients.
- Common side effects include headache, hypotension, dizziness, fatigue, muscle cramps, bradycardia, palpitations, flushing, edema, dyspnea, and dyspepsia.
- Possible interactions with various conditions and drugs.
- Avoid conditions like hypotension, bradycardia, heart block, cardiogenic shock, congestive failure, and hypersensitivity.
Safety Advices
Alcohol
UNSAFE
It is unsafe to consume alcohol with Aloten 5/25.
Pregnancy
CONSULT YOUR DOCTOR
Aloten 5/25 is considered unsafe during pregnancy due to definite evidence of risk to the developing baby. However, in life-threatening situations, a doctor may prescribe it if the benefits outweigh the potential risks. Consult your doctor.
Breastfeeding
CONSULT YOUR DOCTOR
Aloten 5/25 is probably unsafe during breastfeeding. Limited data suggests potential harm to the baby through breast milk. Consult your doctor.
Driving
UNSAFE
Aloten 5/25 may cause side effects affecting your ability to drive, such as dizziness, headaches, nausea, or tiredness. Exercise caution and avoid activities requiring mental focus.
Kidney
CAUTION
Exercise caution with Aloten 5/25 in patients with liver disease. Dose adjustment may be needed. Initiate at a lower dose in patients with liver disease and increase slowly with careful monitoring.
Liver
CAUTION
Use Aloten 5/25 with caution in patients with kidney disease. Dose adjustment may be necessary. Regular blood pressure monitoring is recommended for better dose adjustment.
Similar Products
Uses of Aloten 5
Hypertension.
How does Aloten 5 work?
Aloten 5/25 is a combination of 2 medicines: Amlodipine and Atenolol, which lowers blood pressure effectively. Amlodipine is a calcium channel blocker that works by relaxing blood vessels while atenolol is a beta blocker that works specifically on the heart to slow down the heart rate. Together, they make the heart more efficient at pumping blood throughout the body.
Side Effects of Aloten 5
- Well-tolerated combination.
- Side effects may include fatigue, headache, edema, nausea, drowsiness, anxiety, and depression.
Quick Suggestions:
- Aloten 5/25 treats high blood pressure; continue even if feeling well.
- May cause dizziness; rise slowly to avoid falls.
- Do not stop suddenly; consult the doctor for proper guidance.
- Inform the doctor if pregnant or planning pregnancy.
Indications of Aloten 5
Aloten 5/25 is used for hypertension (high blood pressure), combining Amlodipine and Atenolol.
Pharmacology:
Amlodipine:
- Calcium antagonists inhibit calcium influx into vascular and cardiac muscle.
- Acts more on vascular smooth muscle, reducing peripheral vascular resistance and blood pressure.
- Reduces coronary vasoreactivity, lowering cardiac demand.
Atenolol:
- Cardio-selective beta blocker.
- Reduces blood pressure by lowering cardiac output, plasma renin activity, and sympathetic outflow.
- Reduces myocardial oxygen demand through negative inotropic and negative chronotropic effects.
Dosage & Administration:
- Recommended dosage: One tablet daily (Amlodipine 5 mg & Atenolol 50 mg) or (Amlodipine 5 mg & Atenolol 25 mg).
- Titration of dosage based on therapeutic response.
- In elderly patients, initiate therapy with ½ tablet (Amlodipine 2.5 mg & Atenolol 25 mg).
Interaction
- Amlodipine safely administered with various drugs.
- Atenolol interactions include reduced clearance of Disopyramide and potential additive negative inotropic effects.
- Atenolol has less potential for actions like decreased tissue sensitivity to insulin.
Contraindications
- Hypersensitivity to either component.
- Sinus bradycardia, second and higher degrees of heart block.
- Cardiogenic shock, hypotension, congestive heart failure, poor left ventricular function.
Pregnancy & Lactation
- Atenolol crosses the placenta and is contraindicated in pregnancy.
- Avoid during lactation.
Precautions & Warnings
- Amlodipine has been safely administered with various drugs.
- Atenolol interactions include reduced clearance of Disopyramide and potential additive negative inotropic effects.
- Atenolol has less potential for actions like decreased tissue sensitivity to insulin.
Storage Conditions
- Store in a cool dry place protected from light.
- Keep out of reach of children.
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