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Biotin, also known as vitamin H, is a water-soluble B-complex vitamin essential for numerous physiological processes. It plays a critical role in:
- Fatty acid synthesis
- Amino acid metabolism
- Gluconeogenesis
Biotin functions as a coenzyme for various carboxylases, particularly in the carboxylation of pyruvate and acetyl-CoA, aiding energy production and metabolic balance. It supports the growth and regeneration of skin, hair, and nails by promoting epidermal cell differentiation. At the cellular level, Biotin enhances keratin infrastructure, which is vital for healthy hair and nail structure. Deficiency may lead to dermatitis, hair loss, and aciduria.
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✅ Description:
Biotin is recommended for use in the following conditions:
- Hair thinning and hair loss
- Brittle, weak, or splitting nails
- Skin conditions such as eczema and dermatitis
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✔️ Dosage & Administration
Adults:
Typically, 1–3 tablets daily or as directed by the physician.
Children (with diagnosed deficiency):
Usually presents within 1 week to 2 years of age, with symptoms such as seizures, hypotonia, developmental delay, and coma.
Recommended dose: 5–10 tablets daily, crushed and mixed with water or juice, or as directed by the physician.
Recommended Dietary Allowances (RDA):
| Age Group | Daily Biotin Requirement |
|---|---|
| Infants 0–6 months | 5 mcg |
| Infants 7–12 months | 6 mcg |
| Children 1–3 years | 8 mcg |
| Children 4–8 years | 12 mcg |
| 9–13 years | 20 mcg |
| 14–18 years | 25 mcg |
| Adults (≥19 years) | 30 mcg |
| Pregnancy | 30 mcg |
| Lactation | 35 mcg |
Always follow the physician's instructions.
✔️ Side Effects
- Biotin is generally safe and well-tolerated at the recommended dosages.
- No toxicity observed even at high doses (up to 200 mg orally or 20 mg intravenously per day).
✔️ Drug Interactions
- Anticonvulsants may reduce biotin levels in plasma.
- Antibiotics may interfere with the gut flora responsible for synthesizing biotin.
- Raw egg whites, when consumed in excess, can bind biotin and hinder its absorption.
✔️ Contraindications:
Not recommended for individuals with known allergies to any component of the formulation.
✔️ Use in Pregnancy & Lactation
Limited clinical data available; consult a healthcare provider before use during pregnancy or breastfeeding.
✔️ Storage Instructions
- Keep in a cool, dry place away from moisture and direct sunlight.
- Store out of the reach of children.
⚠️Disclaimer:
At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.
