Generic Name: Pyridoxine Hydrochloride
Manufacturer/Distributor: Beacon Pharmaceuticals Limited
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Indications of Sixvit
Pyridoxine (vitamin B6) is used to prevent or cure vitamin B6 deficiency in persons who don't get enough of it through their diets. The majority of people who follow a healthy diet do not require additional vitamin B6. Low levels of vitamin B6 can be caused by certain illnesses (such as alcoholism, liver disease, hyperactive thyroid, and heart failure) or medications (such as isoniazid, cycloserine, hydralazine, and penicillamine). Vitamin B6 is a vital nutrient in the human body. It is required to keep neurons, skin, and red blood cells healthy. The majority of people who follow a healthy diet do not require additional vitamin B6. Low levels of vitamin B6 can be caused by certain illnesses (such as alcoholism, liver disease, hyperactive thyroid, and heart failure) or medications (such as isoniazid, cycloserine, hydralazine, and penicillamine). Vitamin B6 is a vital nutrient in the human body. It is required to keep neurons, skin, and red blood cells healthy.
Pharmacology
The majority of people who follow a healthy diet do not require additional vitamin B6. Low levels of vitamin B6 can be caused by certain illnesses (such as alcoholism, liver disease, hyperactive thyroid, and heart failure) or medications (such as isoniazid, cycloserine, hydralazine, and penicillamine). Vitamin B6 is a vital nutrient in the human body. It is required to keep neurons, skin, and red blood cells healthy.
Dosage & Administration of Sixvit
Adults:
By Mouth:
For hereditary sideroblastic anemia: Initially, 200-600 mg of vitamin B6 is used. The dose is decreased to 30-50 mg per day after an adequate response.
For vitamin B6 deficiency: In most adults, the typical dose is 2.5-25 mg daily for three weeks then 1.5-2.5 mg per day thereafter. In women taking birth control pills, the dose is 25-30 mg per day.
For abnormally high levels of homocysteine in the blood: For reducing high levels of homocysteine in the blood after childbirth, 50-200 mg of vitamin B6 has been taken alone. Also, 100 mg of vitamin B6 has been taken in combination with 0.5 mg of folic acid.
For preventing macular degeneration: 50 mg of vitamin B6 in the form of pyridoxine has been used daily in combination with 1000 mcg of vitamin B12 (cyanocobalamin) 1000 mcg and 2500 mcg of folic acid for about 7 years.
For hardening of the arteries (atherosclerosis): A specific supplement (Kyolic, Total Heart Health, Formula 108, Wakunga) containing 250 mg of aged garlic extract, 100 mcg of vitamin B12, 300 mcg of folic acid, 12.5 mg of vitamin B6, and 100 mg of L-arginine daily for 12 months.
For kidney stones: 25-500 mg of vitamin B6 has been used daily.
For nausea during pregnancy: 10-25 mg of vitamin B6 taken three or four times per day has been used. In people who don't respond to vitamin B6 alone, a combination product containing vitamin B6 and the drug doxylamine (Diclectin, Duchesnay Inc.) is used three or four times per day. Also, another product containing 75 mg of vitamin B6, 12 mcg of vitamin B12, 1 mg of folic acid, and 200 mg of calcium (PremesisRx, KV Pharmaceuticals) is used daily.
For symptoms of premenstrual syndrome (PMS): 50-100 mg of vitamin B6 is used daily, alone or along with 200 mg of magnesium.
For treating tardive dyskinesia: 100 mg of vitamin B6 per day has been increased weekly up to 400 mg per day, given in two divided doses.
INJECTED INTO THE MUSCLE:
Hereditary sideroblastic anemia: 250 mg of vitamin B6 daily, reduced to 250 mg of vitamin B6 weekly once an adequate response is achieved.
CHILDREN:
BY MOUTH:
For kidney stones: Up to 20 mg/kg daily in children aged 5 years and up.
INJECTED INTO THE VEIN OR MUSCLE:
The daily recommended dietary allowances (RDAs) of vitamin B6 are:
Some researchers think the RDA for women 19-50 years should be increased to 1.5-1.7 mg per day.
The recommended maximum daily intake is:
Interaction of Sixvit
If you take other drugs or herbal products at the same time, the effects of some drugs may alter. This can put you at risk for major side effects or prevent your medications from working properly. These drug interactions can happen, but they don't always happen. Changes in how you take your medications or regular monitoring by your doctor or pharmacist can often prevent or control interactions.
Before beginning therapy with this product, be sure to tell your doctor and pharmacist about all the products you use (including prescription pharmaceuticals, nonprescription drugs, and herbal products) so they can provide you with the best care possible. Do not start, stop, or change the dosage of any other medicines you are taking while using this product without first consulting your doctor.
Side Effects of Sixvit
When used in the recommended doses, pyridoxine has few adverse effects.
Remember that if your doctor has recommended this drug, he or she has determined that the benefit to you outweighs the risk of adverse effects. The majority of people who take this medicine do not have any substantial adverse effects.
When taken in significant dosages over an extended period of time, pyridoxine might induce negative effects. If any of these unlikely but significant side effects develop, contact your doctor right away: headache, nausea, sleepiness, numbness/tingling of arms/legs.
This medicine seldom causes a severe allergic reaction. However, if you detect any symptoms of a major allergic response, such as a rash, itching/swelling (particularly of the face/tongue/throat), extreme dizziness, or problems breathing, seek medical help right once.
Pregnancy & Lactation
Category A: Controlled trials in women have failed to show a risk to the unborn in the first trimester (and no evidence of a risk in subsequent trimesters), and the risk of fetal injury remains remote.
Precautions & Warnings
Tell your doctor or pharmacist if you are allergic to pyridoxine or if you have any other allergies before taking it. Inactive chemicals may be included in this product, causing allergic reactions or other issues. For further information, speak with your pharmacist.
When used in authorized doses, this vitamin has been confirmed to be safe during pregnancy.
Storage Conditions
Protect from light and moisture by storing in a cool, dry place below 30°C. Keep out of children's reach.
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