Allphen 5mg/5ml Oral Solution | 100ml | ePharma
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Allphen 5mg/5ml Oral Solution

Generic: Promethazine Hydrochloride

Type: Syrup

Pack Size: 100ml

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Promethazine hydrochloride 5mg/5ml: 

  • A potent long-acting antihistamine with additional anti-emetic and sedative/calming effects.
  • Indicated in symptomatic treatment of allergic conditions of the respiratory tract and skin.
  • Sensitization reactions to drugs or foreign proteins, anaphylactic reactions.
  • For sedation, allergic rhinitis, urticaria, and insomnia.
  • As an adjunct in pre-operative sedation in surgery and obstetrics.
  • As a pediatric sedative.

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Discount Price: ৳ 28.2
MRP: ৳ 30 6% Off

⪼ Save  ৳: 1.8  in this Product



✅ Description:

  • Allphen is used in the treatment of various allergic conditions, including runny nose, sneezing, congestion, itching, watery eyes, nausea, vomiting, and insomnia in adults. It is also used as a sedative in children aged 5 years and above.
  • Allphen should be taken with or without food, at the same time every day for the prescribed duration.
  • Common side effects include dryness in the mouth, blurred vision, headache, and dizziness.
  • Adult Dose: Oral Allergic conditions: 25 mg at night, increase if necessary. Prophylaxis of motion sickness: 20 mg or 25 mg the night before traveling. Short-term management of insomnia: 20-50 mg at night.
  • Child Dose: Oral Allergic conditions: 2-5 years: 5-15 mg; 5-10 years: 10-25 mg. Prophylaxis of motion sickness: 2-5 years: 5 mg; 5-10 years: 10 mg. Short-term management of insomnia: 2-5 years: 15-20 mg; 5-10 years: 20-25 mg.
  • Renal Dose: Dose reduction may be required for renal impairment.
  • Use with caution in various conditions, including asthma, coronary artery disease, glaucoma, epilepsy, hepatic/renal impairment, Pregnancy, and lactation, Avoid alcohol during treatment.

Safety Advices


Alcohol
UNSAFE

Allphen may cause excessive drowsiness with alcohol.


Pregnancy
CAUTION

Allphen may be unsafe to use during pregnancy. Limited studies in humans suggest harmful effects on the developing baby. Consult your doctor to weigh the benefits and potential risks before prescribing it.


Breastfeeding
SAFE IF PRESCRIBED

Allphen is probably safe to use during breastfeeding. Limited human data suggests no significant risk to the baby. For prolonged use and repeated doses, observe the baby for excessive sleepiness.


Driving
CAUTION

Allphen may decrease alertness, affect vision, or cause sleepiness and dizziness. Avoid driving if these symptoms occur.


Kidney
CAUTION

Allphen is probably safe to use in patients with kidney disease. Limited data suggests dose adjustment may not be needed, but caution is advised in severe cases.


Liver
CAUTION

Allphen should be used with caution in patients with liver disease. Dose adjustment may be needed. Consult your doctor.

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✔️ Uses of Allphen 5mg/5ml Oral Solution

Allergic conditions, Nausea and vomiting, Motion sickness, Insomnia

✔️ How does Allphen 5mg/5ml Oral Solution work?
  • Allphen is an antiallergic medication.
  • Blocks the action of histamine, relieving symptoms of allergy.
  • Works on various areas of the brain to prevent nausea/vomiting and induce relaxation.
✔️ Side Effects of Allphen 5mg/5ml Oral Solution
  • Nervous system disorders: Neuroleptic Malignant Syndrome, somnolence, dizziness, headaches, extrapyramidal effects including muscle spasm, tic-like movements of the head and face.
  • Immune System Disorders: Allergic reactions, including urticaria, rash, pruritus, and anaphylaxis.
  • Skin and Subcutaneous Tissue Disorders: Photosensitivity reaction.
  • Metabolism and Nutrition Disorders: Anorexia.
  • Gastrointestinal Disorders: Epigastric discomfort, dry mouth.
  • Eye Disorders: Blurred vision.
  • Blood and Lymphatic System Disorders: Blood dyscrasias including hemolytic anemia, and agranulocytosis.
  • Renal and Urinary Disorders: Urinary retention.
  • Psychiatric Disorders: Infants, newborns, and premature are susceptible to the anticholinergic effects of promethazine, while other children may display paradoxical hyperexcitability, restlessness, nightmares, and disorientation.
  • Cardiac Disorders: Palpitations, arrhythmias.
  • Vascular Disorders: Hypotension.
  • Hepatobiliary Disorders: Jaundice.
  • General Disorders and Administration Site Conditions: Tiredness.
✔️ Quick Suggestions:
  • Allphen helps treat nausea, vomiting, and insomnia.
  • Caution while driving; can cause dizziness and sleepiness.
  • Avoid alcohol consumption.
  • Use sunscreen or protective clothing to prevent increased skin sensitivity to sunlight.
  • Do not take for more than 7 days.
  • Stop at least three days before an allergy test.
✔️ Pharmacology
  • Promethazine is a phenothiazine derivative that blocks postsynaptic mesolimbic dopaminergic receptors in the brain.
  • Exhibits a strong α-adrenergic blocking effect and depresses the release of hypothalamic and hypophyseal hormones.
  • Competes with histamine for the H1-receptor; muscarinic blocking effect may be responsible for antiemetic activity.
  • Reduces stimuli to the brainstem reticular system.
  • Well absorbed from the gastrointestinal tract.
  • Clinical effects are apparent within 20 minutes after oral administration and generally last four to six hours, although they may persist as long as 12 hours.
✔️ Dosage & Administration of Allphen 5mg/5ml Oral Solution
  • Adults: Initial dose one 25 mg tablet at night; may be increased to two or three 25 mg tablets at night if necessary.
  • In allergic conditions more frequent administration, twice or three times daily, may be necessary, starting with one or two 10 mg tablets and increasing as required.
  • Elderly: No specific dosage recommendations.
  • Children: They may be treated more conveniently by the elixir containing 5 mg/5 ml.
  • As an antihistamine in allergy: Children of 2-5 years: 5-15 mg, Children of 5-10 years: 10-25 mg.
  • In cases where two doses in 24 hours are required, the lower dose stated should be given.
  • As a sedative: Children of 2-5 years: 15-20 mg, Children of 5-10 years: 20-25 mg, Given as a single night-time dose.
✔️ Interaction
  • Allphen 5 mg/5 ml may enhance the action of any anticholinergic agent, tricyclic antidepressant, sedative, or hypnotic.
  • Alcohol should be avoided during drug treatment.
  • Phenergan may interfere with immunologic urine pregnancy tests to produce false-positive or false-negative results.
  • Phenergan should be discontinued at least 72 hours before the start of skin tests using allergen extracts.
✔️ Contraindications:
  • Promethazine is contraindicated for use in children less than two years of age.
  • Hypersensitivity to promethazine or any of the excipients.
  • Phenergan should not be used in patients who are in a coma or suffering from CNS depression of any cause.
  • It must not be given to neonates or premature infants.
  • Phenergan should be avoided in patients who have been taking monoamine oxidase inhibitors within the previous 14 days.
✔️ Pregnancy & Lactation
  • There is epidemiological evidence for the safety of promethazine in pregnancy.
  • Animal studies have shown no hazard; nevertheless, it should not be used in pregnancy unless the physician considers it essential.
  • The use of Phenergan is not recommended in the two weeks before delivery due to the risk of irritability and excitement in the neonate.
  • Available evidence suggests that the amount excreted in milk is insignificant.
  • However, there are risks of neonatal irritability and excitement.
✔️ Precaution & Warnings:
  • The use of promethazine should be avoided in children and adolescents with signs and symptoms suggestive of Reye’s syndrome.
  • Promethazine may thicken or dry lung secretions and impair expectoration.
  • It should, therefore, be used with caution in patients with asthma, bronchitis, or bronchiectasis.
  • Use with care in patients with severe coronary artery disease.
  • Use with care in patients with narrow-angle glaucoma.
  • Use with care in patients with epilepsy.
  • Use with care in patients with hepatic insufficiency.
  • Use with care in patients with renal insufficiency.
  • Caution should be exercised in patients with bladder neck obstruction.
  • Caution should be exercised in patients with pyloric-duodenal obstruction.
✔️ Storage Conditions:
  • Protect from light.
  • Do not use later than the date of expiry.
  • Keep all medicines out of the reach of children.
  • To be dispensed only on the prescription of a registered physician.
Frequently Asked Questions (FAQ)

Symptoms of severe overdose are variable. Characterized in children by various combinations of excitation, ataxia, incoordination, athetosis, and hallucinations. Adults may become drowsy and lapse into a coma. Convulsions may occur in both adults and children; coma or excitement may precede their occurrence. Tachycardia may develop. Cardiorespiratory depression is uncommon. If seen soon enough after ingestion, it should be possible to induce vomiting; alternatively, gastric lavage may be used. Treatment is otherwise supportive with attention to maintenance of adequate respiratory and circulatory status. Convulsions should be treated with diazepam or other suitable anticonvulsant.
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Check our pricing section for Allphen 5mg/5ml Oral Solution price in Bangladesh. After Submitting Order, You will receive a phone call for verification, price and delivery confirmation. We deliver inside/outside Dhaka (Delivery all over Bangladesh). We offer express/urgent medicine delivery inside Dhaka. Do not forget to check discount/cashback offers if you are eligible to avail any.

Disclaimer:
ePharma sole intention is to ensure that its consumers get proper information as musch as possible. Although we do not guarantee the accuracy and the completeness of the information that provided and here information is for informational purposes only. The information contained herein should NOT be used as a substitute for the advice of a qualified physician. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your healthcare professional and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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