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Home Medicines Pain Nalbun Injection 1ml

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Nalbun Injection 1ml

Incepta Pharmaceuticals Ltd.

Generic: Nalbuphine HCl

Type: Injection

Pack Size: 1 Pc

Injection

৳60 ৳56.4

Nalbun Injection is indicated for the relief of moderate to severe pain. It is particularly used in:

Myocardial infarction (MI)
Preoperative and postoperative analgesia
Balanced anesthesia supplementation
Obstetrical analgesia during labor and delivery

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Discount Price: ৳ 56.4

MRP: ৳ 60 6% Off

⪼ Save ৳: 3.6 in this Product

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✅ Description:

Nalbuphine Hydrochloride (Nalbun) is a synthetic opioid analgesic that binds to mu, kappa, and delta receptors, excluding sigma receptors. Its analgesic potency is equivalent to morphine on a milligram basis and is 10 times more potent than pentazocine, but with lower side effects and less abuse potential. The onset of action is 2 to 3 minutes after intravenous administration and less than 15 minutes following intramuscular injection. The plasma half-life is 5 hours, and the duration of analgesic activity ranges from 3 to 6 hours.

Safety Advices

Alcohol

UNSAFE

You are advised not to take alcohol with Nalbuphine as it might cause increased sedation and respiratory depression.

Pregnancy

CONSULT YOUR DOCTOR

Nalbuphine is not recommended for use during pregnancy unless absolutely indicated. Please consult your doctor if you have any concerns.

Breastfeeding

CONSULT YOUR DOCTOR

Nalbuphine should be used with caution during breastfeeding. Please consult your doctor if you have any concerns.

Driving

UNSAFE

Nalbuphine may cause dizziness and drowsiness, which may affect your ability to drive.

Kidney

CAUTION

Exercise caution before using Nalbuphine in case of established liver disease. Please consult your doctor to address any concerns.

Liver

CAUTION

Exercise caution before using Nalbuphine in case of kidney problems. Please consult your doctor to address any concerns.

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✔️ Uses of Nalbun Injection

Pain Relief

✔️ How does Nalbun Injection work?

Nalbun blocks pain signals, so the brain doesn't perceive the severity of pain, hence increasing the body's threshold for pain.

✔️ Side Effects of Nalbun Injection

Commonly well tolerated but may include:

Sedation
Sweating
Nausea
Vomiting
Dizziness
Vertigo
Dry mouth
Headache
Respiratory depression
Dyspnea
Asthma

✔️ Quick Suggestions:

Use Nalbuphine as instructed by your doctor. Never take in greater amounts or more often than prescribed.
It causes sleepiness or drowsiness. If this happens to you, do not drive or use machinery.
Avoid consuming alcohol when taking the Nalbuphine, as it may cause excessive sleepiness or drowsiness.
Inform your doctor if you have ever been diagnosed with kidney or liver problems.
Store opioid pain relievers in a safe place and out of reach of others.

✔️ Indication of Nalbun Injection

Nalbuphine is used for moderate to severe pain.

✔️ Pharmacology

Nalbuphine Hydrochloride is a synthetic, potent analgesic with effects comparable to morphine. It functions primarily as a kappa agonist and partial mu antagonist. Key pharmacological properties include:

Receptor Binding: Binds to mu, kappa, and delta receptors, but not sigma receptors.
Onset of Action: 2 to 3 minutes after intravenous administration; less than 15 minutes after subcutaneous or intramuscular injection.
Plasma Half-Life: Approximately 5 hours.
Duration of Analgesic Activity: Ranges from 3 to 6 hours.

✔️ Dosage & Administration of Nalbun Injection

Adults:

Moderate to Severe Pain:

10-20 mg for a 70 kg patient, via intramuscular or intravenous injection.
Adjust dosage based on pain severity, patient’s physical status, and other medications.
Repeat every 3 to 6 hours as necessary.

Preoperative Anesthesia:

0.1-0.2 mg/kg via intravenous or intramuscular injection.

Obstetrical Analgesia (Labor & Delivery):

0.3-1 mg/kg via intravenous injection over 10-15 minutes.
Maintenance doses of 0.25-0.5 mg/kg as needed.

Intraoperative Analgesia:

0.25-0.5 mg/kg via intravenous injection at 30-minute intervals.

Myocardial Infarction:

10-20 mg via slow intravenous injection.
Repeat after 30 minutes if necessary.

Children (18 months to 15 years old):

Analgesia:
- 0.2 mg/kg body weight, preferably via intravenous or intramuscular injection.
- Maintenance doses every 4 to 6 hours, as determined by a physician.

✔️ Interaction

No hazardous interactions were identified specifically for Nalbun.
Anticipated interactions include additive effects when combined with:
- Narcotic analgesics
- General anesthesia
- Phenothiazines
- Tranquilizers
- Sedatives
- Hypnotics
- CNS depressants (including alcohol)

✔️ Contraindications

Known hypersensitivity to Nalbuphine Hydrochloride.

✔️ Pregnancy & Lactation

Pregnancy Category B: High and rapid placental transfer. Use only if clearly needed.
Lactation: Limited data suggest minimal excretion in maternal milk with no significant clinical effect. Exercise caution when administering to nursing women.

✔️ Precautions & Warnings

Use with caution in:

Impaired respiration
Impaired renal or hepatic function
Biliary tract surgery
Myocardial infarction
Hypotension

✔️ Storage Conditions:

Store below 30°C, protected from light.
Keep out of reach of children.

Frequently Asked Questions (FAQ)

+ Q. Overdose Effects

Symptoms may include sleepiness and mild dyspnea. Treatment involves: Immediate administration of an opiate antagonist (Naloxone or Nalmefene). Supportive measures: oxygen, intravenous fluids, vasopressors.

+ Q. Q. Is there anything I need to be careful about while on therapy with Nalbuphine?

Nalbuphine may cause drowsiness and dizziness, especially in the beginning of the treatment. Do not drive or work with tools or machinery if your alertness is affected. It is not advisable to drink alcohol during treatment with this medicine as it might increase sleepiness.

+ Q. Can I take tion with anti-depressant medications?

+ Q. I suffer from asthma. Can I still use tion

tion is not recommended in those suffering from asthma as there may be a reaction. Consult your doctor before use.

Ratings & Reviews

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ePharma sole intention is to ensure that its consumers get proper information as musch as possible. Although we do not guarantee the accuracy and the completeness of the information that provided and here information is for informational purposes only. The information contained herein should NOT be used as a substitute for the advice of a qualified physician. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your healthcare professional and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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