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Solider 10mg Tablet 10pcs
Solifenacin is a competitive muscarinic receptor antagonist. It primarily targets M3, M1, and M2 receptors, with a high affinity for M3 receptors. By antagonizing the M3 receptor, Solifenacin prevents the contraction of the detrusor muscle, reducing bladder contractions and helping control symptoms of overactive bladder.
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✅ Description:
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✔️ Side Effects: Solider 10
- Common: Dry mouth, blurred vision, constipation, nausea, abdominal pain.
- Less common: Fatigue, dizziness, hallucinations, urinary retention.
- Rare: Colonic obstruction, pruritus, and pruritic rash.
✔️ Dosage & Administration: Solider 10
- Adults and the elderly: Start with 5 mg of Solifenacin once daily. If necessary, increase the dose to 10 mg once daily.
- Children: Not recommended due to the lack of safety and efficacy data.
- Always follow a doctor’s prescription for dosage adjustments.
✔️ Overdose: Solider 10
Overdose can lead to severe anticholinergic effects such as hallucinations, tachycardia, and urinary retention. Treatment includes activated charcoal, gastric lavage, and symptomatic management (e.g., physostigmine for central effects, and beta-blockers for tachycardia).
✔️ Interactions: Solider 10
- Anticholinergic drugs: Caution with other medications that also have anticholinergic effects.
- Cholinergic agonists: May reduce the therapeutic effects of Solider.
- Gastrointestinal motility stimulants: Solider can reduce the effect of drugs like Metoclopramide.
- CYP3A4 inhibitors (e.g., Ketoconazole, Ritonavir): May increase the AUC of Solider; the maximum dose should be limited to 5 mg when used with these drugs.
- CYP3A4 inducers (e.g., Rifampicin): May affect Solider's pharmacokinetics.
- Warfarin, oral contraceptives, and digoxin: No significant interaction was noted.
✔️ Contraindications:
- Hypersensitivity to solifenacin or any component of the formulation.
- Myasthenia gravis, urinary retention, narrow-angle glaucoma, severe gastrointestinal conditions, and severe renal or hepatic impairment.
- Concurrent use with strong CYP3A4 inhibitors (e.g., ketoconazole).
✔️ Pregnancy & Lactation:
- Pregnancy: Use only if necessary as there is insufficient data to confirm safety.
- Breastfeeding: Solifenacin may pass into breast milk and should be avoided during breastfeeding.
✔️ Precautions & Warnings:
- Evaluate other causes of frequent urination before prescribing Solider.
- Caution in patients with gastrointestinal or urinary tract issues, or at risk for urinary retention.
- Renal and hepatic impairment: Dosage adjustment may be necessary.
✔️ Storage Conditions:
Store in a cool, dry place, away from light.
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