Solifenacin is a competitive muscarinic receptor antagonist. It primarily targets M3, M1, and M2 receptors, with a high affinity for M3 receptors. By antagonizing the M3 receptor, Solifenacin prevents the contraction of the detrusor muscle, reducing bladder contractions and helping control symptoms of overactive bladder.
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Overdose can lead to severe anticholinergic effects such as hallucinations, tachycardia, and urinary retention. Treatment includes activated charcoal, gastric lavage, and symptomatic management (e.g., physostigmine for central effects, and beta-blockers for tachycardia).
Store in a cool, dry place, away from light.
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