Flonasin Nasal Spray

Uses of Flonasin Nasal Spray

• Allergic Rhinitis

Hoe does Flonasin Nasal Spray work?

Fluticasone, which is a steroid, and azelastine is an antiallergic agent to reduce the swelling and inflammation of the inner lining of the nose. Flonasin Nasal Spray reduces the symptoms of nose allergy like running nose, irritation in the nose, sneezing, and nasal congestion.

Side Effects of Flonasin Nasal Spray

• Hoarseness Of Voice
• Throat Irritation
• Cough

Quick Suggestions:

Do not use Azelastine Hydrochloride and Fluticasone Propionate Nasal Spray if you:

• Have recently undergone surgery on the nose or paranasal sinuses.
• Have an ulcer or wound in your nose.
• Are suffering from a fungal, bacterial, or viral infection of the airways or throat.
• Have high blood pressure or heart disease.
• Are pregnant or planning a pregnancy?
• Have eye problems like glaucoma or cataract.
• Are below 12 years of age (not recommended for children).
• Have disorders related to the immune system, kidney, or liver.
• Are taking any other steroid medicine orally or through injections?
• Notice the worsening of symptoms after using this spray.

Indication of Flonasin Nasal Spray

Flonasin Nasal Spray is an over-the-counter nasal spray used to treat nasal symptoms like a blocked or runny nose, sneezing, and itchy nose caused by seasonal or perennial allergies. It can also relieve itchy or watery eyes associated with allergies. If prescribed by a doctor, follow their instructions for use. The usual dose is once or twice a day. Avoid getting the spray in your eyes and rinse your eyes thoroughly if it happens. Do not overdose on this medication.

Pharmacology

Azelastine Hydrochloride exhibits histamine H1 receptor antagonist activity in isolated tissues. The major metabolite desmethyl azelastine also has H1 receptor antagonist activity. Fluticasone Propionate is a synthetic trifluoride corticosteroid with anti-inflammatory activity. The exact mechanism by which fluticasone propionate affects the symptoms of allergic rhinitis remains unclear. Corticosteroids have been shown to be involved in the inflammation of a variety of cell types (such as mast cells, eosinophils, neutrophils, macrophages, lymphocytes, etc.) and mediators (such as histamine, eicosanoid, white Trienes, and cytokines) have a wide range of effects.

Dosage & Administration of Flonasin Nasal Spray

• For adults, the recommended dosage of Azelastine Hydrochloride and Fluticasone Propionate Nasal Spray is one spray in each nostril twice daily.
• For pediatric patients, the safety and effectiveness of the nasal spray have not been established for those younger than 6 years of age.

Administration: 

• Use Flonasin Nasal Spray as directed by your doctor.
• Spray it inside both your nostrils one by one.
• Wash your hands before and after using this spray.
• In case your eyes come in contact with this medicine, rinse your eyes with clean water immediately.

Interaction

Individual drug interactions can vary, and it is essential to consult your doctor to check for all possible interactions before starting any medication. 

• Flonasin Nasal Spray may interact with certain medications such as Amitriptyline, Carbamazepine, Clarithromycin, and Ketoconazole.
• Caution should be exercised if you have conditions like Hyperadrenocorticism, infections, ocular herpes infection, eye problems like cataracts or glaucoma, or osteoporosis, as this medication may worsen these conditions.
• There may also be potential interactions with alcohol. It is crucial to discuss your medical history and all the medications you are taking with your doctor to avoid any adverse effects or complications.

This list is not exhaustive, and your doctor can provide you with comprehensive information about drug interactions for your specific case.

Contraindications

If you are allergic to fluticasone, azelastine, or any other ingredient of Flonasin Nasal Spray.

Pregnancy & Lactation

Pregnancy category C. There are no adequate and well-controlled clinical trials using azelastine hydrochloride and fluticasone propionate nasal spray in pregnant women, only azelastine hydrochloride or fluticasone propionate nasal spray. It should be used for pregnant women only when the potential benefit to the mother justifies the potential risk to the fetus.

Precautions & Warnings

• Avoid spraying directly into the eyes; if the drug gets into the eyes, flush with water for at least 10 minutes.
• This medication may cause drowsiness; avoid operating heavy machinery or tasks requiring mental alertness and coordination.
• Do not use if you have a history of recent nasal ulcers, nasal surgery, or any nasal trauma.
• Long-term use may cause glaucoma or cataracts.
• Corticosteroids in the nasal spray may lead to immunosuppression; notify healthcare providers if you experience any symptoms of tuberculosis, viral, bacterial, fungal, or parasitic infections, or ocular herpes simplex.
• Children using this medication should be monitored regularly due to the potential reduction in growth velocity.
• For breastfeeding women, it is unknown whether the medication is distributed in breast milk, so use caution during lactation.
• Do not share the bottle with anyone else so that you do not spread germs.

Storage Conditions

Store below 25°C. Keep away from light. Do not store it in the refrigerator. Keep out of reach of children.