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Cariso 250 Tablet 1 Strip
Cariso is prescribed for:
- Alleviating discomfort linked to acute, painful musculoskeletal conditions in adults
- Promoting sedation and easing anxiety in patients suffering from severe pain
- Serving as a supportive therapy in physical rehabilitation for musculoskeletal injuries
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✅ Description:
Carisoprodol acts as an indirect agonist of the GABA-A receptor, enhancing chloride ion conductance in the central nervous system. This results in sedative, anxiolytic, and muscle-relaxant effects. Its active metabolite, meprobamate, contributes to its calming and muscle-relaxing properties. Carisoprodol works centrally by interrupting nerve signals between the brain/spinal cord and muscles, thereby relieving muscle spasms. It does not act directly on skeletal muscle fibers.
✔️ Dosage & Administration
Adults (18+ years):
250–350 mg orally, three times a day and at bedtime.
Maximum recommended treatment duration: 2 to 3 weeks
Special Populations:
Use cautiously in individuals with hepatic or renal impairment or reduced CYP2C19 enzyme activity.
✔️ Pregnancy & Lactation
Pregnancy Category C: Use only if clearly needed.
May cause reduced milk production or infant sedation when used by breastfeeding mothers. Exercise caution.
✔️ Overdose Management
- Cariso overdose may cause profound CNS depression, coma, respiratory failure, hypotension, and seizures.
- Do NOT induce vomiting due to sedation risk.
- Consider gastric lavage within 1 hour of ingestion.
- Supportive care includes fluid resuscitation, vasopressors, and airway management (including intubation if needed).
- Seizures should be managed with IV benzodiazepines; if persistent, phenobarbital may be considered.
✔️ Side Effects
Drowsiness
Dizziness
Headache
✔️ Drug Interactions
- Concurrent use with CNS depressants (e.g., alcohol, opioids, benzodiazepines, tricyclic antidepressants) may enhance sedative effects.
- CYP2C19 inhibitors (e.g., Omeprazole, Fluvoxamine) may increase Cariso levels.
- CYP2C19 inducers (e.g., Rifampin) may reduce Cariso exposure.
✔️ Contraindications
- Known hypersensitivity to carisoprodol or carbamate derivatives (e.g., meprobamate)
- History of acute intermittent porphyria
✔️ Precautions & Warnings
- May impair alertness—avoid driving or operating heavy machinery.
- Increased sedative effects when used with alcohol or other CNS depressants.
- Risk of dependence, withdrawal, and abuse with prolonged use.
- Seizures may occur, particularly in overdose or abrupt withdrawal.
✔️ Storage
Store at 20°C–25°C in a cool, dry environment away from direct light. Keep out of reach of children.
⚠️Disclaimer:
At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.
