Virux Oral Suspension

✔️ Uses of Virux Oral Suspension

• Herpes simplex virus infections
• Chickenpox
• Herpes labialis
• Shingles
• Genital herpes infection

✔️ How does Virux Oral Suspension work?

Virux 70 ml works by preventing the multiplication of the virus in human cells. This action stops the virus from producing new viruses and ultimately helps clear up the infection.

✔️ Side Effects of Virux Oral Suspension

Possible side effects include rash, gastrointestinal disturbances, increased bilirubin and liver-related enzymes, elevated blood urea and creatinine, decreased hematological indices, headache, neurological reactions, and fatigue.

✔️ Quick Suggestions:

• Incorporate heart-healthy omega-3 fatty acids into your diet. You can find these in foods like fish, flaxseeds, and walnuts. Also, use low-fat cooking oils like olive oil, soybean oil, canola oil, and coconut oil.
• Including turmeric or yellow mustard in your diet can help prevent constipation, a side effect of some antiviral drugs. Additionally, increase your fluid intake to stay well-hydrated.
• Ensure you get an adequate amount of Vitamin D, either through sunlight exposure or dietary sources. Fresh air and sunlight can help improve the symptoms of herpes infection.
• Try to minimize emotional and physical stress by spending time with family or engaging in activities that make you happy. Reducing stress can be beneficial for your overall health.
• Consume a balanced and nutritious diet to support your overall well-being. Additionally, ensure you get at least 8 hours of sleep a day for a faster recovery.
• If you're going out in strong sunlight, wear a lip balm with SPF 15 or higher. ACICLOVIR can make your skin sensitive to UV rays and sunlight.

✔️ Indications:

Virux Oral Suspension is indicated for the treatment of various herpes virus infections, including herpes simplex virus (types I and II) and varicella-zoster virus infections (such as herpes zoster and chickenpox). It is used for the treatment of initial and recurrent genital herpes, as well as herpes labialis (cold sores) and herpes simplex infections of the skin and mucous membranes. Additionally, it is used to prevent herpes simplex infections in immunocompromised individuals.

✔️ Pharmacology

Virux Oral Suspension contains aciclovir, which is a purine derivative that interferes with DNA synthesis, limiting viral replication. It primarily works by blocking the action of the virus-encoded thymidine kinase enzyme, which is necessary for viral DNA replication. It is transformed into its pharmacologically active form, Aciclovir Triphosphate, within virus-infected cells. Aciclovir is absorbed through the gastrointestinal tract and distributed to various body tissues. It is eliminated through the kidneys via glomerular filtration and tubular secretion.

✔️ Dosage & Administration of Virux Oral Suspension

• Treatment of initial herpes simplex: 200 mg five times daily for five days.
• For immunocompromised patients, the adult dose is 400 mg five times daily for five days (longer if new lesions appear during treatment or if healing is incomplete; increase the dose to 800 mg five times daily for genital herpes in immunocompromised).
• Prevention of recurrence of herpes simplex: 200 mg four times daily for adults.
• Prophylactic treatment of herpes simplex in immunocompromised patients: 200 to 400 mg four times daily for adults.
• Treatment of varicella (chickenpox): 800 mg four times daily for adults and children over 40 kg.
• Treatment of herpes zoster (shingles): 800 mg five times daily for seven days.
• Treatment of initial rectal (proctitis) herpes infections: 400 mg five times daily for ten days.
• Renal Impairment: Dosage adjustment is recommended for patients with severe renal impairment.

✔️ Interaction

Probenecid can increase plasma levels of Aciclovir and raise the risk of toxicity.

✔️ Contraindications

Virux Oral Suspension should not be used in patients with a known hypersensitivity to Aciclovir.

✔️ Pregnancy & Lactation

Category B pregnancy. Use during pregnancy should be considered only if the potential benefit outweighs the risk to the fetus. Caution is advised when administering it to nursing mothers.

✔️ Precautions & Warnings

Use with caution in patients with renal impairment. Dose adjustments should be made based on creatinine clearance. Neonates should have their neutrophil count monitored at least twice weekly.

✔️ Storage Conditions

Store below 25°C, protect from light and moisture and keep out of the reach of children.