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Gentamicin 0.3% Cream is a versatile topical antibiotic used for a wide range of skin infections and conditions. It is effective against both Gram-positive and Gram-negative bacteria, making it a valuable treatment option.
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✅ Description:
Gentin 0.3% Cream is indicated for the treatment of the following conditions:
- Burns
- Eczema
- Seborrheic dermatitis
- Ecthyma
- Excoriation
- Folliculitis
- Furunculosis
- Insect bites and stings
- Lacerations and abrasions
- Paronychia
- Pyoderma gangrenosum
- Skin cysts and abscesses
- Stasis ulcers and infected skin ulcers
- Bacterial, fungal, or viral superinfection
- Sycosis barbae
- Minor surgical wounds
- Infected contact dermatitis caused by susceptible organisms
Safety Advices
Alcohol
No interaction found/established
Pregnancy
CONSULT YOUR DOCTOR
Gentin 0.3% Cream is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breastfeeding
CONSULT YOUR DOCTOR
Gentin 0.3% Cream is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving
No interaction found/established
Kidney
No interaction found/established
Liver
No interaction found/established
Relevant Products / প্রাসঙ্গিক পণ্য
✔️ Uses of Gentin 0.3% Cream
Treat Bacterial skin infections
✔️ How does Gentin 0.3% Cream work?
Gentamicin is an antibiotic. It stops bacterial growth by preventing the synthesis of essential proteins required by bacteria to carry out vital functions.
✔️ Side Effects of Gentin 0.3% Cream
- Itching
- Redness
- Swelling
- Other signs of irritation
✔️ Quick Suggestions:
- Your doctor has prescribed Gentamicin to cure your infection and improve your symptoms.
- Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection come back and harder to treat.
- It is given as a drip (intravenous infusion) or as an injection directly into a vein or a muscle.
- Use caution while driving or doing anything that requires concentration as Gentamicin may cause dizziness.
- Your doctor may get regular blood, urine, or hearing tests while you are on this medication.
- Your doctor will ensure that you are well hydrated before and during treatment with this medicine.
- Inform your doctor if you are pregnant, planning to conceive, or breastfeeding.
- Discontinue Gentamicin and inform your doctor immediately if you get a rash, itchy skin, swelling of your face and mouth, or difficulty in breathing.
✔️ Indication of Gentin 0.3% Cream
Gentamicin is used in the treatment of bacterial infections.
✔️ Pharmacology
Gentamicin Sulfate is an aminoglycoside antibiotic. It has proven bactericidal activity against a broad spectrum of Gram-positive and Gram-negative pathogens, including:
- E. coli
- Klebsiella
- Proteus
- Pseudomonas aeruginosa
- Penicillin-resistant strains of Staph. aureus
The mechanism of action involves interference with bacterial protein synthesis.
✔️ Dosage & Administration of Gentin 0.3% Cream
- Dosage: Apply 3 times daily.
- Instructions:
- Wash the affected area with soap and water.
- Dry thoroughly before application.
- Remove any crusts present before applying the ointment for maximum contact with the infecting organisms.
- Note: Follow the doctor's prescription for application instructions.
✔️ Interaction
Synergistic Interactions:
- Antibiotics:
- Ampicillin
- Benzylpenicillin
- Other β-lactam antibiotics
- These combinations can enhance the effectiveness of Gentamicin in treating bacterial infections.
Increased Risk of Severe Respiratory Depression:
- Concurrent Use with:
- Anesthetics
- Opioids
- This can significantly increase the risk of severe respiratory depression.
Reduced Renal Clearance:
- With:
- Zalcitabine
- This interaction can reduce the renal clearance of zalcitabine.
Induction of Hypocalcaemia:
- With:
- Biphosphonates
- This combination may induce hypocalcemia.
Contraindicated Combinations:
- With:
- Agalsidase alfa
- Agalsidase beta
- These can inhibit alpha-galactosidase activity.
Potentially Fatal Interactions:
- Increased Incidence of Ototoxicity:
- With:
- Ethacrynic acid
- Furosemide
- This combination can significantly increase the risk of ototoxicity (damage to the ear).
- With:
Potentiation of Nephrotoxicity:
- With:
- Cephalosporins
- Ciclosporin
- Cisplatin
- Vancomycin
- Hydrocortisone
- Indometacin
- These medications can potentiate the nephrotoxic (kidney-damaging) effects of Gentamicin.
Potentiation of Neuromuscular Blocking Agents:
- Gentamicin can potentiate the effects of neuromuscular blocking agents, which can lead to increased muscle relaxation and potentially severe respiratory depression.
✔️ Contraindications
- Hypersensitivity to Gentamicin.
- Pregnancy and myasthenia gravis.
✔️ Pregnancy & Lactation
- Pregnancy: Category D. Use during pregnancy only if needed, due to potential risk.
- Lactation: Gentamicin can be excreted in small amounts in breast milk. Breastfeeding should be discontinued during treatment.
✔️ Precautions & Warnings
- Do not apply to patients with hypersensitivity to Gentamicin.
- Use cautiously in patients with suspected glaucoma.
✔️ Storage Conditions:
- Store below 30°C.
- Protect from light.
