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Home Medicines Infection Exiben Powder for Suspension

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Exiben Powder for Suspension

Benham Pharmaceuticals Ltd.

Generic: Cefixime trihydrate

Type: Suspension

Pack Size: 50ml

Suspension

৳210 ৳197.4

Exiben (Cefixime trihydrate) is an orally active cephalosporin antibiotic with bactericidal activity against a wide range of Gram-positive and Gram-negative organisms. It is indicated for the treatment of acute infections caused by susceptible microorganisms, including:

Upper Respiratory Tract Infections (URTI), e.g., otitis media
Other URTI where the causative organism is known or suspected to be resistant to other antibiotics
Lower Respiratory Tract Infections, e.g., bronchitis
Urinary Tract Infections, e.g., cystitis, cystourethritis, pyelonephritis

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MRP: ৳ 210 6% Off

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✅ Description:

Exiben is an antibiotic from the cephalosporin group used to treat various bacterial infections. It is effective against respiratory tract infections, urinary tract infections, ear infections, sinus infections, throat infections, and certain sexually transmitted diseases. Exiben can be taken with or without food, but it should be taken regularly at evenly spaced intervals as prescribed by the doctor. Completing the full course is crucial, even if symptoms improve before completion. It doesn't work against viral infections like flu or the common cold.

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✔️ Uses of Exiben

Pneumonia, Pharyngitis, Typhoid fever, Susceptible infections, Sinusitis, Otitis media, Tonsillitis, Soft tissue infections, Respiratory tract infections, Acute Exacerbations of Chronic bronchitis, Gonococcal urethritis, Acute bronchitis.

✔️ How Exiben works?

Inhibits bacterial cell wall formation, leading to bacterial cell death.

✔️ Side Effects of Exiben

Nausea
Stomach pain
Indigestion
Diarrhea

✔️ Quick Suggestions:

Take Exiben regularly and complete the full course.
Take with food to avoid an upset stomach.
Diarrhea may occur, but it should stop after completing the course.
Avoid alcohol during Exiben treatment.
Discontinue and inform your doctor if you experience rash, itching, swelling, or difficulty breathing.

✔️ Pharmacology

Cefixime is a third-generation semisynthetic cephalosporin antibiotic.
Bactericidal against a broad spectrum of gram-positive and gram-negative bacteria.
Interferes with the synthesis of the bacterial cell wall.
Highly stable in the presence of Beta-lactamase enzymes.

✔️ Dosage & Administration of Exiben

Administration:

May be taken with or without food. May be taken with food or milk to reduce GI discomfort.

Adult Dose:

Acute Bronchitis & Acute Exacerbations of Chronic Bronchitis, Otitis Media, Pharyngitis/Tonsillitis, Uncomplicated Urinary Tract Infections Adult: 200 or 400 mg daily as a single dose or in two divided doses. Gonorrhea: 400 mg as a single dose. Typhoid fever: 20 mg/kg body weight daily in two divided doses. The usual treatment is 7 days, up to 14 days for severe infections.

Child Dose:

Varies with age and condition. Typically, 8 mg/kg/day if <50 kg q12–24h. Typhoid Fever: 15-20 mg/kg/day PO divided q12hr for 7-14 days; not to exceed 400 mg/day.

Renal Dose:

Dose reduction is necessary for renal impairment. Max: 200 mg daily if CrCl <20 ml/min.

✔️ Interaction

Increases in prothrombin times were noted in some patients.
Caution is advised in patients receiving anticoagulant therapy.

✔️ Contraindications

Known hypersensitivity to cephalosporin antibiotics.

✔️ Pregnancy & Lactation

Limited data; use during pregnancy only if needed.
Not known if Cefixime is excreted in human milk; caution during lactation.

✔️ Precautions & Warnings

Administer with caution to patients hypersensitive to other drugs.
Use cautiously in penicillin-sensitive patients due to partial cross-allergenicity.
Caution in patients with markedly impaired renal function.
Avoid in pregnancy or nursing mothers unless essential.

✔️ Storage Conditions

Keep below 30ºC, protected from light and moisture.
Keep out of the reach of children.

Frequently Asked Questions (FAQ)

+ Q. Overdose Effects?

Gastric lavage may be indicated; no specific antidote. Not removed significantly by dialysis.

+ Q. Precaution?

History of allergy to penicillins; pregnancy, lactation; renal failure; GI disease.

+ Q. Side Effects?

Generally well-tolerated; most adverse reactions are mild and self-limiting. Common side effects include gastrointestinal disturbances, headache, dizziness, and hypersensitivity reactions. Pseudomembraneous colitis has been reported. Changes in liver and renal function tests are reversible.

+ Q. Dosage & Administration?

Absorption is not significantly modified by the presence of food. The usual course of treatment is 7 days, extendable to 14 days if necessary. Adults and children over 10 years: 200-400 mg daily, as a single dose or in two divided doses. Elderly: Same dose as recommended for adults; adjust in severe renal impairment. Children: Dosage varies by age; a general guide for daily doses in suspension volume is provided. Dosage in Renal Impairment: Adjust based on creatinine clearance.

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