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Fibril 300mg Capsule 1 Strip
Gemfibrozil 300 mg Capsule-
- Hypertriglyceridemia (high levels of triglycerides)
- Hyperlipidemia (elevated cholesterol or fat levels in the blood)
✅ Description:
Fibril is a medication primarily prescribed for managing high levels of cholesterol and triglycerides in the blood. It plays a vital role in cardiovascular health by reducing "bad" cholesterol (LDL) and triglycerides while simultaneously increasing "good" cholesterol (HDL). This combined effect helps in lowering the risk of serious heart-related events such as heart attacks and strokes.
✔️ Fibril contains Gemfibrozil, a lipid-regulating agent. It works by:
- Inhibiting the breakdown of fat in fat cells, thus decreasing the flow of fatty acids to the liver.
- It reduces the liver’s production and secretion of very low-density lipoproteins (VLDL), which are rich in triglycerides.
- Increasing HDL (good cholesterol), which helps clear cholesterol from the bloodstream. This action helps to maintain a healthier lipid profile, which is crucial in preventing cardiovascular complications.
✔️ Side Effects
- Nausea, vomiting
- Abdominal pain, flatulence
- Diarrhea
- Increased liver enzyme levels
- Indigestion (dyspepsia)
- Fatigue, headache, dizziness
- Rare but Serious Side Effects:
- Muscle pain or weakness (potential signs of rhabdomyolysis, especially if taken with statins)
- Visual disturbances
- Liver issues (yellowing of the skin/eyes, dark urine)
- Blood disorders like anemia, leukopenia
- Gallstones (cholelithiasis)
- Skin rash or eczema
✔️ Dosage and Administration:
- The standard adult dosage is 600 mg taken twice daily.
- It is important to take Fibril on an empty stomach, ideally 30 minutes before meals.
- Always follow your doctor’s prescribed dose and duration.
✔️ Words of Advice:
- Even if you feel fine, don’t stop taking the medication unless advised by your doctor.
- Regular monitoring of cholesterol levels and liver function is important during treatment.
- Fibril is most effective when used alongside a comprehensive lifestyle plan, including:
- A low-fat, heart-healthy diet
- Regular physical activity
- Smoking cessation
- Moderation of alcohol intake
- Weight management
✔️ Missed Dose:
If a dose is missed:
Take it as soon as you remember.
However, if it’s almost time for your next scheduled dose, skip the missed dose.
Do not double up to make up for a missed dose.
✔️ Interaction
- May enhance the effect of oral anticoagulants (e.g., warfarin), increasing the risk of bleeding.
- Can increase blood levels of repaglinide (an anti-diabetic drug), leading to hypoglycemia.
- When used with cyclosporine, it may raise the risk of kidney damage.
- Serious interaction risk with HMG-CoA reductase inhibitors (statins)—may cause severe muscle damage (rhabdomyolysis).
✔️ Contraindications:
- Known hypersensitivity to Gemfibrozil or any of the excipients
- Severe liver or kidney dysfunction
- Gallbladder disease
- During pregnancy and breastfeeding
- In children or neonates
✔️ Precautions & Warnings
- Rule out and manage underlying conditions like diabetes or hypothyroidism before starting therapy.
- Use cautiously in patients with renal impairment; monitor kidney function closely.
- Avoid combining with statins due to risk of muscle toxicity.
- Periodic lipid profile assessments are recommended.
- Stop use if there's no significant improvement after 3 months.
✔️ Storage:
- Store at room temperature (20-25°C).
- Protect from direct light and moisture.
- Keep out of reach of children.
Disclaimer:
ePharma sole intention is to ensure that its consumers get proper
information as musch as possible. Although we do not guarantee the
accuracy and the completeness of the information that provided and
here information is for informational purposes only.
The information contained herein should NOT be used as a substitute
for the advice of a qualified physician. This may not cover
everything about particular health conditions,
lab tests, medicines, all possible side effects, drug interactions,
warnings, alerts, etc. Please consult your healthcare professional
and discuss all your queries related to any disease or medicine. We
intend to support, not replace, the doctor-patient relationship.
