Verquv 10 | 1 Strip

✔️ Indications:

Verquv is indicated to reduce the risk of cardiovascular death and heart failure (HF) hospitalization following a hospitalization for heart failure or need for outpatient IV diuretics, in adults with symptomatic chronic HF and ejection fraction less than 45%.

Dosage and administration

Precautions

Special waming: Embryo-Fetal Toxicity

Vericiguat may cause fetal harm when administered to a pregnant woman. Obtain a pregnancy test before the start of treatment. Advise females of reproductive potential of the potential risk to a fetus, to use effective contraception during treatment with vericiguat and for at least one month after the final dose.

Side effects

Most common side effects are hypotension and anemia.

Contraindications

Vericiguat is contraindicated in patients with known hypersensitivity to it or any other components of this product. It is also contraindicated in patients with concomitant use of other soluble guanylate cyclase (sGC) stimulators and in pregnancy.

Drug interactions

Drug interaction with medication: Vericiguat is not recommended in patients with concomitant use of other soluble guanylate cyclase (sGC) stimulators. Concomitant use of vericiguat with PDE-5 inhibitors is not recommended because of the potential for hypotension.

✔️ Use in pregnancy & lactation

Pregnancy: Vericiguat may cause fetal harm when administered to a pregnant woman and is contraindicated during pregnancy.

Lactation: There are no data on the presence of vericiguat in human milk, the effects on the breastfed infant, or the effects on milk production. Because of the potential for serious adverse reactions in breastfed infants from vericiguat, advise women not to breastfeed during treatment with vericiguat.

✔️ Route of administration:

Verquv should be taken in oral route with food. For patients who are unable to swallow whole tablets, Verquv® may be crushed and mixed with water immediately before administration or as directed by the physician. The recommended starting dose of Verquv is 2.5 mg once daily. Double the dose of Verquv approximately every 2 weeks to reach the target maintenance dose of 10 mg once daily, as tolerated by the patient.

✔️ Storage

Store below 30°C in a dry place, protected from light. Keep away from the reach of children.