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Entresto 200mg 10pcs
Entresto contains sacubitril (a neprilysin inhibitor) and valsartan (an angiotensin receptor blocker). Sacubitril increases levels of beneficial peptides that support cardiovascular and kidney function, while valsartan blocks the angiotensin II receptor, reducing its effects on blood vessels and aldosterone release.
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✅ Description:
Entresto is used to:
- Lower the risk of cardiovascular death and hospitalizations in patients with chronic heart failure (NYHA Class II-IV) and reduced ejection fraction.
- Treat symptomatic heart failure with systemic left ventricular systolic dysfunction in pediatric patients aged one year and older.
- It is typically used with other heart failure treatments, replacing ACE inhibitors or ARBs.
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✔️ Uses of Entresto 200
Heart Failure
✔️ Dosage & Administration: Entresto 200
For Adults:
- Starting dose: 49/51 mg twice daily.
- Increase to: 97/103 mg twice daily after 2 to 4 weeks, if tolerated.
- A lower starting dose (24/26 mg twice daily) is recommended for patients new to ACE inhibitors/ARBs, or those with severe kidney or moderate liver impairment.
For Pediatric Patients (1 year and older):
- Dosage varies by weight, starting from 1.6 mg/kg twice daily for those under 40 kg.
- Patients over 50 kg follow the adult dosage schedule.
- Pregnancy & Lactation: Should not be used due to potential harm to the fetus or nursing infant.
- Pediatric Use: Safe for ages 1 and older; not established for infants under 1 year.
- Elderly Patients: No significant differences in response.
- Liver & Kidney Impairment: Dose adjustments may be required for moderate/severe impairment.
✔️ Side Effects: Entresto 200
Common side effects include:
- Angioedema, low blood pressure, kidney impairment, high potassium levels, cough, and dizziness.
✔️ Drug Interactions:
- Avoid use with ACE inhibitors, ARBs, or aliskiren in diabetic patients.
- Potassium-sparing diuretics may increase potassium levels.
- NSAIDs may heighten the risk of kidney impairment.
- Lithium toxicity risk may increase.
✔️ Entresto should not be used in:
- Patients with known hypersensitivity to any component.
- Those with a history of angioedema from ACE inhibitors or ARBs.
- Within 36 hours of switching from an ACE inhibitor.
- Patients taking aliskiren with diabetes.
✔️ Warnings & Precautions:
- Angioedema: Discontinue immediately if it occurs.
- Hypotension (low blood pressure): Monitor closely, especially in patients with kidney disease.
- High potassium levels: Periodic monitoring required.
- Liver & Kidney Function: Monitor in at-risk patients.
✔️ Storage:
Store in a cool and dry place, protect from light. Keep out of reach of children.
Disclaimer:
ePharma sole intention is to ensure that its consumers get proper
information as musch as possible. Although we do not guarantee the
accuracy and the completeness of the information that provided and
here information is for informational purposes only.
The information contained herein should NOT be used as a substitute
for the advice of a qualified physician. This may not cover
everything about particular health conditions,
lab tests, medicines, all possible side effects, drug interactions,
warnings, alerts, etc. Please consult your healthcare professional
and discuss all your queries related to any disease or medicine. We
intend to support, not replace, the doctor-patient relationship.
