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Fungin B Topical Cream
Betamethasone 0.05% + Clotrimazole 1% topical preparation is used for the treatment of inflammatory fungal infections of the skin, such as:
- Tinea pedis (Athlete’s foot)
- Tinea cruris (Jock itch)
- Tinea corporis (Ringworm)
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✅ Description:
Clotrimazole is a broad-spectrum antifungal agent that treats superficial fungal infections caused by dermatophytes, yeasts, and Malassezia furfur. It works by inhibiting the synthesis of ergosterol, a crucial sterol in the fungal cell membrane. This disruption weakens the cell membrane, leading to fungal cell death.
Betamethasone dipropionate is a corticosteroid that provides anti-inflammatory, antipruritic (anti-itch), and vasoconstrictive effects. While its precise mechanism of action is not fully understood, it helps reduce inflammation and associated symptoms.
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✔️ Side Effects
Possible adverse reactions include:
- Common:
- Paresthesia (tingling or numbness) (1.9%)
- Burning and dry skin (1.6%)
- Less Common (<1%):
- Rash
- Edema (swelling)
- Secondary infections
- Stinging sensation
✔️ Dosage & Administration
- Apply a sufficient amount of the cream to the affected area and surrounding skin twice daily (morning and evening).
- Duration of treatment:
- Tinea cruris & Tinea corporis: 2 weeks
- Tinea pedis: 4 weeks
- Prolonged use beyond four weeks is not recommended.
- Safety and effectiveness have not been established for children under 12 years of age.
Use only as directed by a registered physician.
✔️ Drug Interactions
No known drug interactions have been reported.
✔️ This topical preparation should not be used in patients with:
- Hypersensitivity to clotrimazole, betamethasone, other corticosteroids, or imidazoles.
- Facial rosacea
- Acne vulgaris
- Perioral dermatitis
- Perianal and genital pruritus
- Napkin eruptions (diaper rash)
- Bacterial or viral infections
Prolonged use of topical corticosteroids can lead to HPA (Hypothalamic-Pituitary-Adrenal) axis suppression. If this occurs, the medication should be gradually withdrawn or the frequency of application should be reduced.
Children are more susceptible to systemic side effects due to their higher skin surface-to-body mass ratio.
✔️ Pregnancy & Lactation
- There is limited safety data on the use of this cream during pregnancy.
- Animal studies show no teratogenic effects of clotrimazole, but high oral doses have been toxic to fetuses.
- Corticosteroids applied topically to pregnant animals have been linked to fetal abnormalities.
- Use in pregnancy should be considered only if the potential benefits outweigh the risks and should be limited in quantity and duration.
- Whether the ingredients pass into breast milk; caution is advised for nursing mothers.
✔️ Storage Conditions
- Store below 30°C.
- Keep away from light and moisture.
- Keep out of the reach of children.
Disclaimer:
ePharma sole intention is to ensure that its consumers get proper
information as musch as possible. Although we do not guarantee the
accuracy and the completeness of the information that provided and
here information is for informational purposes only.
The information contained herein should NOT be used as a substitute
for the advice of a qualified physician. This may not cover
everything about particular health conditions,
lab tests, medicines, all possible side effects, drug interactions,
warnings, alerts, etc. Please consult your healthcare professional
and discuss all your queries related to any disease or medicine. We
intend to support, not replace, the doctor-patient relationship.
