Prolert 20mg 10pcs

Indications of Prolert 20

A type of antidepressant known as Prolert 20 is a member of the SSRI (selective serotonin reuptake inhibitor) drug class. It is frequently prescribed to treat mental health issues like panic disorder and obsessive-compulsive disorder as well as depression. By elevating mood and easing tension and anxiety, Prolert 20 aids in the recovery of many people suffering from depression. It also lessens binge eating and purging in the treatment of the eating disorder bulimia nervosa (vomiting).

Pharmacology

An antidepressant that is a phenylpropanolamine derivative is fluoxetine hydrochloride. It has no chemical affinity for tetracycline, tricyclic, or any other type of antidepressant. According to research, fluoxetine increases the concentration of synaptic serotonin in the central nervous system (CNS) by selectively inhibiting serotonin (5-HT) reuptake at the presynaptic neuronal membrane.

Administration & Dosage of Prolert 20

A dose increase may be considered if there has been no clinical improvement for several weeks. It is recommended to administer doses greater than 20 mg twice daily—at noon and in the morning—and not to go over 80 mg per day. As with other antidepressants, it may take 4 weeks or longer for the full antidepressant effect to take effect. similar to many other drugs.

Interaction of Prolert 20

Serotonergic drugs may cause serotonin syndrome (e.g. triptans, TCAs, fentanyl, tramadol, lithium, buspirone, tryptophan). Aspirin, NSAIDs, warfarin, and other anticoagulants may increase the risk of bleeding. Phenytoin levels in the blood may rise.

Contraindications

There have been reports of serious, occasionally fatal reactions in patients receiving Fluoxetine in combination with monoamine oxidase inhibitors, including hyperthermia, rigidity, myoclonus, autonomic instability with potential rapid fluctuations of vital signs, and changes in mental status, including extreme agitation progressing to delirium and coma (MAOIs)

Side Effect of Prolert 20

• Nausea
• Vomiting
• Dyspepsia
• Dry mouth
• Diarrhea 
• Anxiety nervousness
• Insomnia/drowsiness
• Fatigue 

Other symptoms include excessive sweating, pruritus, and skin rashes, all of which are linked to liver, kidney, and lung involvement. Fluoxetine therapy should be stopped in any patient who develops a skin rash, according to the experts.

Pregnancy & Lactation

Pregnancy: No teratogenicity or adverse effects were discovered in animal studies. Fluoxetine should only be used in pregnancy if it is clearly needed, as animal reproductive studies are not always predictive of human responses.

Precautions & Warnings

• Fluoxetine should be used with caution and in low doses in patients with impaired hepatic or renal function because it is metabolized in the liver and eliminated through the kidneys. 
• Due to its epileptogenic effect, it should be used with caution in patients who have epilepsy or a history of similar disorders. 
• Diabetic patients should exercise caution when taking fluoxetine because it has the potential to affect glycemic control.

Storage Conditions

Keep the temperature below 30°C and away from light and moisture. Keep out of children's reach.