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Laxante 10
Sodium Picosulfate is a stimulant laxative of the triarylmethane group. After oral administration, it is activated by colonic bacteria, acting locally in the colon. The active form stimulates nerve endings in the intestinal wall, inducing:
- Colonic peristalsis
- Water and electrolyte accumulation in the colonic lumen
- Stool softening and stimulation of defecation
This action helps restore the natural "call to stool" and reduces transit time.
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✅ Description:
Laxante is indicated for:
- Constipation of any etiology
- Relief from prolonged and recurrent constipation
- Bowel clearance before surgery, childbirth, or radiological investigations
Note: Use under the guidance of a registered physician.
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✔️ Uses
- Constipation
✔️ Dosage and Administration
For oral use. Recommended to take it at night for evacuation the following morning. Begin with the lowest dose and adjust as needed (do not exceed the maximum daily dose).
10 mg Tablet
- Adults and children over 10 years: 5-10 mg/day
- Children (4-10 years): 2.5-5 mg/day
✔️ Chronic overdosage may lead to:
- Chronic diarrhea
- Abdominal pain
- Hypokalemia
- Secondary hyperaldosteronism
- Renal calculi
- Renal tubular damage and metabolic alkalosis
✔️ Interaction
- Increased risk of electrolyte imbalance with concomitant use of diuretics or adreno-corticosteroids (especially with excessive doses).
- Reduced laxative effect when used with antibiotics.
✔️ Possible side effects include:
- Common: Diarrhea, abdominal pain/cramps, nausea, vomiting
- Others: Dizziness, syncope (vasovagal response), hypersensitivity
✔️ Do not use in patients with:
- Ileus or intestinal obstruction
- Severe, acute abdominal conditions (e.g., appendicitis)
- Acute inflammatory bowel disease
- Severe dehydration
- Hypersensitivity to Sodium Picosulfate or any components
✔️ Pregnancy and Lactation
- No reported harmful effects during pregnancy or to the fetus.
- Avoid in the first trimester.
- The active metabolite and its glucuronides are not excreted in breast milk.
✔️ Precautions and Warnings
- Prolonged excessive use may result in:
- Fluid and electrolyte imbalance
- Hypokalemia
- Caution for patients with:
- Alcoholism
- Liver disease
- Epilepsy
- To be used with care during pregnancy, breastfeeding, and in children.
✔️ Storage Conditions
- Store below 30°C.
- Protect from light and moisture.
- Keep out of reach of children.
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here information is for informational purposes only.
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everything about particular health conditions,
lab tests, medicines, all possible side effects, drug interactions,
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and discuss all your queries related to any disease or medicine. We
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