Cosmotrin 0.25% Cream

Uses of Cosmotrin 0.25% Cream

• Treatment of Acne
• Acute promyelocytic leukemia

Side Effects of Cosmotrin 0.25% Cream

• Dryness and peeling of the skin
• Redness and itching of the skin
• Burning or stinging sensation on the skin
• Increased sensitivity to sunlight
• Blistering, crusting, or swelling of the skin
• Mild skin irritation
• Mild skin discoloration or darkening
• Acne breakouts

How does Cosmotrin 0.25% Cream work?

Cosmotrin is a form of vitamin A. When applied on the skin, it reduces oil production in the skin, replenishes acne-prone skin, and helps keep your pores open.

Quick Suggestions:

• Cosmotrin 0.25% Cream is typically applied topically to the affected areas of the skin once a day, usually in the evening.
• It is important to avoid using it around the eyes, mouth, and other sensitive areas of the face.
• It is important to avoid sun exposure while using this cream because it can make your skin more sensitive to sunlight and lead to sunburn. Protect your skin by wearing protective clothing and using sunscreen when going outside.
• Regular exercise can improve your mood and self-esteem, although it doesn't directly clear acne. After exercising, make sure to take a shower to remove sweat, as it can irritate acne.
• Make sure to wash your hair regularly and avoid letting it fall across your face, as hair can contribute to acne breakouts.
• Opt for water-based cosmetic products and ensure you completely remove your makeup before going to bed.
• It is crucial not to apply Cosmotrin 0.25% Cream in larger amounts than prescribed, as doing so will not yield quicker or better results but may cause peeling intense redness, or discomfort in the skin.
• Refrain from squeezing spots or attempting to clean blackheads, as this can worsen them and potentially result in permanent scarring.
• It is important to avoid using other skin care products that may be irritating or drying to the skin while using tretinoin. This includes other topical acne medications, astringents, and exfoliants.

Indication

For topical application within the treatment of skin break-out vulgaris in which comedones, papules, and pustules prevail.

Pharmacology

While the exact mechanism of action of Tretinoin is not fully understood, current evidence suggests that when applied topically, Tretinoin reduces the adhesion between cells in the follicular epithelium, leading to a decrease in the formation of micro-comedones. Additionally, Tretinoin stimulates cellular division and increases the turnover of follicular epithelial cells, which helps eliminate comedones, papules, and pustules.

Dosage and Administration of Cosmotrin 0.25% Cream

• This cream should be applied sparingly to the whole affected area once or twice daily.
• The skin should be thoroughly cleaned and dried before application. Patients should be advised that 6 to 8 weeks of treatment may be required before a therapeutic effect is observed.
• Moisturizers and cosmetics may be used during treatment with Tretinoin cream but should not be applied to the skin at the same time.
• Astringent toiletries should be avoided.

Interaction

• Cosmotrin 0.25 can potentially interact with certain medications and substances. It may interact with retinoids like isotretinoin, which are vitamin A-related drugs. Additionally, interactions may occur with photosensitizing agents such as aminolevulinic acid, methoxsalen, performer, and verteporfin. Sensitizers like methyl aminolevulinate, keratolytic agents such as benzoyl peroxide, salicylic acid, and sulfur, as well as antiseptics like resorcinol, may also interact with Cosmotrin 0.25. It is important to inform your doctor about all medications, including over-the-counter drugs, supplements, and topical products, that you are using to avoid potential interactions.
• Regarding drug-food interactions, no specific interactions have been reported forCosmotrin 0.25.
• If you have eczema or any other skin condition, it is important to inform your doctor before using Cosmotrin 0.25, as they can provide guidance on the appropriate use of the cream based on your specific condition.

Contraindications

Tretinoin is contraindicated for individuals who have a profound sensitivity or allergy to any of the ingredients present in the cream. Furthermore, this cream should not be used by patients who have a personal or family history of cutaneous epithelioma, which refers to skin cancer. If you fall into any of these categories, it is important to avoid using Tretinoin and consult with your healthcare professional for alternative treatment options.

Pregnancy & Lactation

There is insufficient evidence regarding the safety of topically applied Tretinoin during human pregnancy. However, Tretinoin has been associated with teratogenicity (causing birth defects) when used systemically (internally). Therefore, it is recommended to avoid using the cream during pregnancy and lactation. It is important to consult with your healthcare professional for alternative treatments or precautionary measures if you are pregnant or breastfeeding.

Precautions & Warnings

• If you have any allergies to tretinoin or any other medications, it is important to inform your doctor before using TCosmotrin 0.25. If you experience worsening skin irritation, redness, burning, or stinging at the application site, discontinue the use of the cream and consult a doctor.
• For individuals who are pregnant, planning to become pregnant, or breastfeeding, it is advisable to consult a doctor before using Cosmotrin 0.25% due to the limited evidence on its safety in these situations.
• To protect your skin from increased sensitivity to the sun, avoid sun exposure as much as possible, use sunscreen lotion, and wear protective clothing when going outdoors.
• It is important to use Cosmotrin 0.25% in the prescribed amounts and avoid applying it in larger quantities, as this will not lead to quicker or better results but may cause peeling noticeable redness, or skin discomfort.
• When using Cosmotrin 0.25, exercise caution if using it in conjunction with medicated or abrasive soaps, cleansers, shampoos, astringents, products with high alcohol concentrations, electrolysis, hair depilatories, waxes, or other topical medications, as they may increase skin irritation.

Storage Conditions

Protect from light and moisture by storing below 30°C. Keep the medicine out of children's reach.