Mixtard 30 Vial 100IU/ml

Indications

Diabetes type 1 patient are all given treatment. treatment for type 2 diabetics who are unable to control their blood sugar levels through diet or oral hypoglycemic drugs.

For the initial stabilization of diabetes in diabetic patients with diabetic ketoacidosis, hyperosmolar non-ketotic syndrome, and times of stress like serious illnesses or major surgery. preventing and managing pregnancy-related diabetes.

Pharmacology

A human insulin produced using recombinant DNA is called insulin human (rDNA). Its structure and capabilities are the same as those of insulin found in nature. The hormone insulin controls the metabolism of glucose and enhances its uptake and utilization by the liver, muscles, and adipose tissue. By accelerating glycogenesis and inhibiting gluconeogenesis, it also lowers blood glucose levels.

Insulin Human (rDNA) 30/70 & Insulin Human 50/50 (rDNA) The drug starts to work within 30 minutes of injection, reaches peak levels in 2-8 hours, and lasts for about 24 hours.

Dosage 

• Between 0.5 and 1.0 IU/kg is the typical range of the total daily insulin requirement for type 1 diabetic patients undergoing maintenance therapy.
• In prepubescent children, it typically ranges between 0.7 and 1.0 IU/kg, whereas in cases of insulin resistance, such as those associated with obesity or puberty, the daily insulin requirement may be significantly higher.
• For patients with type 2 diabetes, starting doses are frequently lower, ranging from 0.3 to 0.6 IU/kg/day.
• Due to the unique characteristics of each patient, the insulin dosage form, dosage, and administration time vary.
• Additionally, the dosage is influenced by what you eat, how you work, and how hard you exercise.
• As a result, patients should only use insulin as directed by their physician.

Administration

• Administer within 15 minutes of or right after eating.
• Administer subcutaneously in the abdominal wall, thigh, or upper arm.
• More quickly than from other injection sites, the abdominal wall receives a subcutaneous injection.

Interaction

When taking oral contraceptives, adrenal cortical hormone, thyroid hormone, and other medicines that cause blood glucose to rise, you may need to raise your Insulin dosage. When utilizing hypoglycemic medicines such as salicylate, sulfanilamide, and other anti-depressants that cause a drop in blood glucose, the insulin dosage should be lowered.

Contraindications

Patients with hypoglycemia or who are allergic to insulin or any of the excipients.

Side Effects

Hypoglycemia is the most prevalent side effect of insulin therapy, and symptoms of hypoglycemia can strike without warning. There have been a few reports of adverse reactions such as redness, swelling, and itching. It normally vanishes after a few days. In other cases, other factors, such as disinfectant or poor injection technique, may be to blame for the allergy rather than insulin.

Pregnancy & Lactation

Insulin treatment for diabetes is not restricted during pregnancy since insulin does not cross the placental barrier. The infant is not at risk from the mother's insulin medication.

Precautions & Warnings

Hyperglycemia can result from insufficient doses or withdrawal, particularly in type 1 diabetes. If the insulin dose is excessively high compared to the insulin needed, hypoglycemia might result. Hypoglycemia can be caused by skipping a meal or engaging in unplanned, vigorous exercise.

Storage Conditions

Refrigerate between 2°C and 8°C. Do not allow yourself to become frozen. If you don't need to refrigerate insulin for immediate use, keep it in a cold place away from heat and light. Insulin can be stored at room temperature for up to a month. effect of insulin.